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TranscriptomicsRNA-Seq analysis of primary AML specimens exposed to AhR modulating agents
The goal of the study was to identify genes that are directly or indirectly coregulated by the AhR pathway in primary human AML cells. Patient AML cells were treated for 16 hours with the two indirubin derivatives 6-bromoindirubin-3'oxime (BIO), 1-Methyl-6-bromoindirubin-3'oxime (MeBIO), the AHR-ant...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-48843 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of human adult peripheral blood populations
Generate transcriptomic atlas of healthy peripheral blood subpopulations RNA-Seq performed on sorted granulocytes, monocytes, B-cells, T-cells, total WBC, CD34+ cells Leucegene Project, IRIC
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-51984 | biostudies-arrayexpress
ProteomicsDDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition
In efforts to identify additional therapeutic targets for Acute Myeloid Leukemia (AML), we performed a high-throughput screen that includes 56 primary specimens tested with 10,000 structurally diverse small molecules. One specific hit, called S656 acts as a molecular glue degrader (MGD), that mediat...
ORGANISM(S): Homo sapiens (Human) 
2025-03-18 | PXD061850 | Pride
Molecular glue degrader Cdk12 Ddb1 Cyclin k Acute myeloid leukemia 
UnknownCost-Utility Analysis of Accelerated and Standard Strategies for Renal Replacement Therapy Initiation.
Not available
S-EPMC12495491 | biostudies-literature
UnknownFactors associated with adverse haemodynamic events during the STARRT-AKI trial: a post-hoc secondary analysis.
Not available
S-EPMC12751851 | biostudies-literature
UnknownA Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial.
Not available
S-EPMC9404618 | biostudies-literature
UnknownRegional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.
Not available
S-EPMC10878545 | biostudies-literature
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