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The centromere, defined by the enrichment of CENP-A (a Histone H3 variant) containing nucleosomes, is a specialised chromosomal locus that acts as a microtubule attachment site. To preserve centromere identity, CENP-A levels must be maintained through active CENP-A loading during the cell cycle. A c...
ORGANISM(S): Homo sapiens (Human) 
2024-05-15 | PXD047345 | Pride
Apicomplexan parasites rely on actin-based motility for host cell invasion and for their dissemination. Although previous studies implicate formin 1 (FRM1) in governing this process in Toxoplasma, the mechanisms that position it at the cell apex and regulate its activity during the transition from i...
ORGANISM(S): Toxoplasma gondii ME49 
2025-11-04 | PXD068228 | Pride
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