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MetabolomicsGREM1 Deficiency induced Bone Marrow Adipose Niche promotes B-cell Acute Lymphoblastic Leukemia Disease Progression
Relapse and disease progression are the primary causes of treatment failure and subsequent mortality in children B-cell acute lymphocytic leukemia (B-ALL). At diagnosis and during treatment, the bone marrow adipose microenvironment is commonly observed in pediatric leukemia. However, the relationshi...
2024-09-23 | MTBLS10103 | MetaboLights
MetabolomicsBone Marrow Metabolomics (part II)
Not available
ORGANISM(S): Mus musculus 
ST000201 | MetabolomicsWorkbench
MetabolomicsBone Marrow Metabolomics (part I)
Not available
ORGANISM(S): Mus musculus 
ST000182 | MetabolomicsWorkbench
TranscriptomicsExpression Data from Bone Marrow Progenitor-Derived Adipocytes, White Adipocytes and Brown Adipocytes.
We have identified a population of adipocytes in fat tissue that arise from bone marrow-derived progenitor cells. We used microarrays to compare the global gene expression patterns of the bone marrow progenitor-derived adipocytes as well as conventional white and brown adipocytes to evaluate the rel...
ORGANISM(S): Mus musculus 
2010-01-08 | E-GEOD-19757 | biostudies-arrayexpress
ProteomicsLiquid chromatography-tandem mass spectrometry analysis of bone marrow from the ground or running rats
Exercise can prevent osteoporosis and improve immune function, but the mechanism remains unclear. To explore the key factors involved in these two processes, we collected bone marrow from ground and running rats and then conducted liquid chromatography-tandem mass spectrometry.
ORGANISM(S): Rattus norvegicus (Rat) 
2023-10-17 | PXD033807 | Pride
Fat metabolism Exercise Immunity Bone marrow fat Bone metabolism Lipolysis 
TranscriptomicsExpression data of bone marrow and peripheral adipocytes from leptin deficient mice and obese mice fed with a high fat diet
The aim of this study was to characterize the obesity-related gene expression profiles between bone marrow adipocytes and peripheral white adipocytes from obese mice fed with high fat diet and leptin deficient mice Alterations of gene expression with high fat diet and in mice lacking leptin were ana...
ORGANISM(S): Mus musculus 
2011-11-29 | E-GEOD-27017 | biostudies-arrayexpress
TranscriptomicsGenechip analysis of bone marrow osteoprogenitors exposed to microgravity
In March 2006, murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on their osteogenic potential in a three-dimensional environment. BMSC were grown in porous bioceramic Skelite disks (Φ 9 mm x T 1.2 mm). ...
ORGANISM(S): Mus musculus 
2010-10-15 | E-GEOD-17696 | biostudies-arrayexpress
TranscriptomicsGene expression profiling on FePro labeled bone marrow stromal cells
Superparamagnetic iron oxide nanoparticles (SPION) are increasingly used to label human bone marrow stromal cells (BMSCs, also called mesenchymal stem cells) to monitor their fate by in vivo MRI and histology after Prussian blue (PB) staining. SPION-labeling appears to be safe as assessed by in vitr...
ORGANISM(S): Homo sapiens 
2011-01-24 | E-GEOD-20431 | biostudies-arrayexpress
MetabolomicsLipidomics study of different fat deposition sites in wuzhishan pigs with double knockout of APOE/LDLR
Apolipoprotein E (APOE) and the low-density lipoprotein receptor (LDLR) play a key role in regulating lipoprotein transport and cholesterol homeostasis. However, their roles in porcine fat deposition and adipose tissue remodelling are not well understood. This study utilised wild-type (WT) and APOE/...
2026-09-09 | MTBLS15330 | MetaboLights
TranscriptomicsExpression data from mouse bone marrow adipocytes with age
The aim of this study was to characterize the age-related gene expression profiles between bone marrow adipocytes and peripheral white adipocytes. Alterations of gene expression with aging were analyzed in bone marrow and peripheral white adipocytes isolated from C57BL/6J male mice using Affymetrix ...
ORGANISM(S): Mus musculus 
2011-11-29 | E-GEOD-25905 | biostudies-arrayexpress
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