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ProteomicsOvercoming steric restrictions of VRC01 HIV-1 neutralizing antibodies through immunization
Broadly HIV-1 neutralizing VRC01-class antibodies target the CD4-binding site of Env. They are derived from VH1-2*02 antibody heavy chains paired with rare light chains expressing five amino acid long CDRL3s. They have been isolated from infected subjects but have not yet been elicited by immunizati...
ORGANISM(S): Human immunodeficiency virus 1 Homo sapiens 
2020-05-26 | PXD015168 | Pride
Immunization Hiv N276 Glycan Vrc01 426c core Mice Antibody Bnab 
ProteomicsProteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4+ regulatory T cells
The CD4+ regulatory T (Treg) cell lineage comprises thymus-derived (t)Treg cells and peripherally induced (p)Treg cells. As a model for Treg cells, studies employ TGF-β-induced (i)Treg cells generated from CD4+ conventional T (Tconv) cells in vitro. Here, we describe the relationship of iTreg cells ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-28 | PXD038302 | Pride
Human Ttreg Tconv Itreg Conventional t cell Thymus-derived regulatory t cell Induced regulatory t cell Treg Tgf-beta Regulatory t cell 
UnknownWhy it is hard to find genes associated with social science traits: theoretical and empirical considerations.
Not available
S-EPMC3778125 | biostudies-literature
UnknownHemoglobinopathy screening in primary care in the Netherlands: exploring the problems and needs of patients and general practitioners.
Not available
S-EPMC10133269 | biostudies-literature
UnknownCancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?
Not available
S-EPMC3376736 | biostudies-literature
UnknownOral fosfomycin versus ciprofloxacin in women with E.coli febrile urinary tract infection, a double-blind placebo-controlled randomized controlled non-inferiority trial (FORECAST).
Not available
S-EPMC6280543 | biostudies-literature
UnknownWhat makes knowledge translation work in practice? Lessons from a demand-driven and locally led project in Cameroon, Jordan and Nigeria.
Not available
S-EPMC10694879 | biostudies-literature
TranscriptomicsGlucosylated hydroxymethyluracil (DNA base J) prevents transcriptional read-through in Leishmania
Some T's in nuclear DNA of trypanosomes and Leishmania are hydroxylated and glucosylated to yield base J (?-D-glucosyl-hydroxymethyluracil). In Leishmania about 99% of J is located in telomeric repeats. We show here that most of the remaining J is located at chromosome-internal RNA Polymerase II ter...
ORGANISM(S): Leishmania major 
2011-10-15 | E-GEOD-32976 | biostudies-arrayexpress
TranscriptomicsDNA copy number profiling of canine osteosarcoma
Identification of DNA copy number imbalances in 22 spontaneous canine osteosarcoma cases using array comparative genomic hybridization (aCGH) analysis
ORGANISM(S): Canis familiaris 
2013-11-01 | E-MTAB-1986 | biostudies-arrayexpress
UnknownLong-term cognitive performance and its relation to anti-inflammatory therapy in a cohort of survivors of severe COVID-19.
Not available
S-EPMC9482799 | biostudies-literature
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