Sort   by:  
 Page size 
ProteomicsLabel-free, quantitative analysis of PKA-dependent phosphoproteome changes in Trypanosoma brucei
Protein kinase A (PKA), the main effector of second messenger cAMP, is highly conserved among eukaryotes and a paradigm for the mechanisms of regulation of protein kinases by ligands. The unique PKA holoenzymes in the phylogenetically distant protozoan parasite Trypanosoma are unresponsive to cAMP i...
ORGANISM(S): Trypanosoma brucei 
2019-02-25 | PXD012245 | Pride
Protein kinase a  pka  trypanosoma  7-cyano-7-deazainosine  label-free quantitative phosphoproteome analysis 
ProteomicsIdentification of ESAG4-interacting proteins in Trypanosoma brucei bloodstream forms
How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. Flagellar cAMP signaling is implicated in interaction of the unicellular parasite Trypanosoma brucei with its hosts. The seco...
ORGANISM(S): Trypanosoma brucei brucei 
2022-08-31 | PXD025412 | Pride
Adenylate cyclase Cyclase-interacting protein Camp signaling Gfp trap 
ProteomicsIdentification of CARP3-interacting proteins in Trypanosoma brucei bloodstream forms and procyclic forms
How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip me...
ORGANISM(S): Trypanosoma brucei brucei 
2022-08-31 | PXD025398 | Pride
Cyclase-interacting protein Adenylate cyclase Carp3 Camp response protein Gfp trap 
ProteomicsQuantitative proteomics upon CARP3 knock down in Trypanosoma brucei bloodstream forms
How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip me...
ORGANISM(S): Trypanosoma brucei brucei 
2022-08-31 | PXD025401 | Pride
Cyclase-interacting protein Adenylate cyclase Carp3 Camp response protein 
ProteomicsLabel-free quantitative analysis of PKA-dependent proteome changes in Trypanosoma brucei
Protein kinase A (PKA), the main effector of second messenger cAMP, is highly conserved among eukaryotes and a paradigm for the mechanisms of regulation of protein kinases by ligands. The unique PKA holoenzymes in the phylogenetically distant protozoan parasite Trypanosoma are unresponsive to cAMP i...
ORGANISM(S): Trypanosoma brucei 
2019-02-25 | PXD009073 | Pride
Protein kinase a 7-cyano-7-deazainosine Pka Trypanosoma Label-free quantitative proteome analysis 
ProteomicsBioID-based proteomic analysis of CARP3-proximal proteins in Trypanosoma brucei bloodstream forms
How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip me...
ORGANISM(S): Trypanosoma brucei 
2022-08-17 | PXD025357 | Pride
Cyclase-interacting protein Flagellar member 8 Adenylate cyclase Carp3 Camp response protein Flam8 
Sort   by:  
 Page size