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UnknownChemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling.
Not available
S-EPMC11779957 | biostudies-literature
ProteomicsMolluscum Contagiosum Virus Protein MC089 Inhibits Interferon Regulatory Factor 3 Activation
Molluscum contagiosum virus (MCV) is a human-specific poxvirus that causes a highly common but mild infection characterised by distinctive and persistent papular skin lesions. These lesions can persist for long periods without an effective clearance response from the host. MCV, like all poxviruses, ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD054178 | Pride
Molluscum contagiosum virus  mc089  innate immunity  ikkε  tbkbp1  nap1  mavs. 
UnknownMolluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO.
Not available
S-EPMC10062130 | biostudies-literature
ProteomicsElongator is required for pattern recognition receptor and type I interferon signaling in macrophages.
Innate immune detection of pathogens by macrophages requires a rapid and large scale mobilisation of cellular resources towards an appropriate immune response, mainly involving altered protein expression. Pathogen recognition is mediated by pattern recognition receptor (PRR) sensing of conserved mic...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-22 | PXD064630 | Pride
Innate immunity  interferon  interferon regulatory factor (irf)  lipopolysaccharide (lps)  macrophage  pattern recognition receptor (prr)  stat transcription factor  toll-like receptor 4 (tlr4)  virus  elongator 
UnknownElongator is required for pattern recognition receptor and type I interferon signaling in macrophages.
Not available
S-EPMC12702316 | biostudies-literature
UnknownMolluscum contagiosum virus protein MC089 inhibits interferon regulatory factor 3 activation.
Not available
S-EPMC11338640 | biostudies-literature
UnknownMyeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7.
Not available
S-EPMC8748983 | biostudies-literature
ProteomicsMultilevel proteomics reveals common and specific host perturbations by Monkeypox and Vaccinia viruses
The global spread of Monkeypox virus (MPXV) has resulted in the urgent need for an in-depth molecular characterization of the virus infection. Multiple omics studies on Vaccinia virus have extended our knowledge of poxvirus pathophysiology (REFs). Nevertheless, there are no comparative studies that ...
ORGANISM(S): Homo sapiens (Human) Monkeypox virus Orthopoxvirus 
2024-07-25 | PXD040889 | Pride
Human Poxvirus Lc-ms Monkeypoxvirus 
UnknownNon-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Not available
S-EPMC6127031 | biostudies-literature
ProteomicsMultilevel proteomics reveals common and specific host perturbations by Monkeypox and Vaccinia viruses (full proteome)
The global spread of Monkeypox virus (MPXV) has resulted in the urgent need for an in-depth molecular characterization of the virus infection. Multiple omics studies on Vaccinia virus have extended our knowledge of poxvirus pathophysiology (REFs). Nevertheless, there are no comparative studies that ...
ORGANISM(S): Homo sapiens (Human) Monkeypox virus Orthopoxvirus 
2024-07-25 | PXD040811 | Pride
Human Poxvirus Shotgun-proteomics Vaccinia virus Monkeypox virus 
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