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Skeletal muscle atrophy is a serious and highly prevalent condition that remains poorly understood at the molecular level. Previous work found that skeletal muscle atrophy involves an increase in skeletal muscle Gadd45a expression, which is necessary and sufficient for skeletal muscle fiber atrophy...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-05-17 | MSV000079730 | MassIVE
Here, we used a method, SNO trapping by triaryl phosphine (SNOTRAP), combined with mass spectrometry, to identify SNO-proteins present in post-mortem brain samples. Following analysis of SNO-proteins in samples of 11 human brains from patients LBD and controls, we detected 943 SNO-proteins and 1,552...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD036703 | Pride
A causal relationship between mitochondrial metabolic dysfunction and neurodegeneration has been strongly implicated in synucleinopathies, including Parkinson’s disease (PD) and Lewy body dementia (LBD), but the underlying molecular basis is not fully understood. Here, using human induced pluripoten...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD036797 | Pride
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