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TranscriptomicsRNA-seq of human oesophageal adenocarcinoma OE19 cell line following PPARGC1A knock-down and 24 hour lapatinib treatment
To determine genes regulated by the transcriptional co-activator PPARGC1A in OAC cells and whether PPARGC1A activity is altered by lapatinib we performed RNA-seq on OE19 cells treated with non-targeting siRNA or siRNA targeting PPARGC1A. 24 hours post-transfection, cells were also treated with eithe...
ORGANISM(S): Homo sapiens 
2022-09-26 | E-MTAB-10317 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human oesophageal adenocarcinoma OE19 cell line treated with lapatinib
To investigate changes to gene expression associated with resistance to lapatinib, we performed ATAC-seq on OE19 cells treated with 500 nM lapatinib for 1, 7 and 35 days and vehicle control (DMSO) for 1 day.
ORGANISM(S): Homo sapiens 
2022-09-26 | E-MTAB-10304 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of WTC-CRISPRi human induced pluripotent stem cells
We performed 3' single-cell RNA-seq using the 10X Genomics Chromium (version 1 chemistry) system on ~19,000 undifferentiated human IPSCs to explore the cellular heterogeneity of a seemingly homogeneous cell population.
ORGANISM(S): Homo sapiens 
2018-08-17 | E-MTAB-6687 | biostudies-arrayexpress
TranscriptomicsRNA-seq of islet, FACS- sorted CD45+Ly6C-CD11B+CD11C+F4/80+ cells from C57bl6/J male mice that were treated with low dose streptozotocin (STZ) or acetate buffer
The experiment was designed to obtain a broader unbiased view of the changes in islet macrophages following low dose STZ challenge. Mice were purchased from Jackson Laboratory (Bar Harbor, ME). 16-20-week-old C57BL/6J males were given 30 mg/kg STZ or acetate buffer (control) i.p. (intraperitoneal ...
ORGANISM(S): Mus musculus 
2019-11-01 | E-MTAB-7234 | biostudies-arrayexpress
UnknownPhase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients.
Not available
S-EPMC12727275 | biostudies-literature
ProteomicsExcretory/secretory proteome of the female and male hookworm Ancylostoma ceylanicum
Proteomic profiling of the excreted / secreted products from adult female and male hookworm Ancylostoma ceylanicum, including a media-only control sample.
ORGANISM(S): Ancylostoma Ceylanicum Blank Sample 
2022-10-14 | PXD037410 |
UnknownA novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study.
Not available
S-EPMC4271131 | biostudies-literature
ProteomicsTransgenic hookworm secretes anti-tetrodotoxin human single chain antibody
We generated transgenic hookworms secreting anti-TTX countermeasure s16-HuScFv. Proteomics samples were generated from host hamster serum
ORGANISM(S): Ancylostoma Ceylanicum Mesocricetus Auratus 
2026-01-17 | PXD073224 |
UnknownStudy design and methods of the BoTULS trial: a randomised controlled trial to evaluate the clinical effect and cost effectiveness of treating upper limb spasticity due to stroke with botulinum toxin type A.
Not available
S-EPMC2611962 | biostudies-literature
TranscriptomicsResveratrol supplementation does not improve metabolic function in non-obese women with normal glucose tolerance
Resveratrol has been reported to improve metabolic function in metabolically-abnormal rodents and humans, but has not been studied in non-obese people with normal glucose tolerance. We conducted a randomized, double-blind, placebo-controlled trial to evaluate the metabolic effects of 12 weeks of re...
ORGANISM(S): Homo sapiens 
2013-01-02 | E-GEOD-41168 | biostudies-arrayexpress
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