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TranscriptomicsGene expression profiling of mouse splenic Dendritic cells subsets
We describe a novel subset of CD8+ DCs in lymphoid organs of naïve mice characterized by expression of the CX3CR1 chemokine receptor. CX3CR1+CD8+ DCs lack hallmarks of classical CD8+ DCs, including IL12 secretion, the capacity to cross-present antigen and their developmental independence of the tran...
ORGANISM(S): Mus musculus 
2010-07-28 | E-GEOD-23212 | biostudies-arrayexpress
UnknownAnaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein.
Not available
S-EPMC1347276 | biostudies-literature
TranscriptomicsIdentification of FOXP3-dependent transcripts in human FOXP3 expressing Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37253 | biostudies-arrayexpress
TranscriptomicsFOXP3 binding sites in promoter regions of human Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37252 | biostudies-arrayexpress
TranscriptomicsDefinition of the Pseudomonas aeruginosa Anr and Dnr Regulons
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable D...
ORGANISM(S): Pseudomonas aeruginosa 
2010-07-07 | E-GEOD-17179 | biostudies-arrayexpress
UnknownInfluenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control.
Not available
S-EPMC10846710 | biostudies-literature
UnknownA spatiotemporal atlas of the lepidopteran pest Helicoverpa armigera midgut provides insights into nutrient processing and pH regulation.
Not available
S-EPMC8785469 | biostudies-literature
TranscriptomicsTranscription profiling of mouse interleukin-10-deficient model for inflammatory bowel disease in C57Bl/6J and C3H/HeJBir strain backgrounds
Abstract: Interleukin-10-deficient (Il10-/-) mice serve as a model for inflammatory bowel disease (IBD). The severity of colitis strongly depends on the inbred strain carrying the disrupted Il10 gene: C3H/HeJBir (C3) confers disease susceptibility, whereas C57BL/6J (B6) confers resistance. Genome-wi...
ORGANISM(S): Mus musculus 
2007-12-04 | E-GEOD-2172 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Treg cell versus their controls in human and mouse
We applied Affymetrix GeneChip technology for expression profiling of CD4+CD25+ (Treg) T cells versus their naive CD4+CD25- controls to obtain more information about the underlying molecular mechanisms involved in Treg specific immune suppression Experiment Overall Design: Expression profiles from: ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4571 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Th cells expressing Foxp3 and UBD ectopically
Expression analysis revealed that UBD is a down-stream element of Foxp3 in human activated regulatory CD4+ T cells (Treg). Experiment Overall Design: Comparison of expression profiles measured in naturally occuring regulatory T-cells (Treg), Foxp3 and UBD transformed Th cells versus their controls w...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4527 | biostudies-arrayexpress
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