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TranscriptomicsIdentification of metastamirs as metastasis-associated microRNAs in clear cell renal cell carcinomas
Background/Objective: MicroRNAs (miRNAs) play a pivotal role in cancerogenesis and cancer progression, but their specific role in metastasis of clear cell renal cell carcinomas (ccRCCs) as so-called metastamirs is still limited. Based on microRNA microarray analyses from normal (n=12) and cancerous ...
ORGANISM(S): Homo sapiens 
2013-02-26 | E-GEOD-37989 | biostudies-arrayexpress
TranscriptomicsWhole-genome expression data from normal FVB mouse lung tissue, transgenic cyclin E overexpressing (CEO) normal mouse lung tissue, and transgenic CEO lung adenocarcinomas
FVB mice were engineered to express wild-type human cyclin E under control of the human surfactant C promoter (CEO mice; Ma et al, PNAS 2007). These mice develop spontaneous lung tumors, which were shown to be adenocarcinoma by histological analysis. Here we compare whole-genome RNA expression lev...
ORGANISM(S): Mus musculus 
2013-04-04 | E-GEOD-45744 | biostudies-arrayexpress
UnknownFDA-approved Abl/EGFR/PDGFR kinase inhibitors show potent efficacy against pandemic and seasonal influenza A virus infections of human lung explants.
Not available
S-EPMC10034449 | biostudies-literature
UnknownClinical characteristics and treatment modalities in uremic and non uremic calciphylaxis - a dermatological single-center experience.
Not available
S-EPMC10773653 | biostudies-literature
ProteomicsProtein abundance of AKT and ERK pathway components governs cell-type-specific regulation of proliferation
Signaling through the AKT and ERK pathways controls cell proliferation. However, the integrated regulation of this multistep process, involving signal processing, cell growth and cell-cycle progression, is poorly understood. Here we study different murine hematopoietic cell types, in which AKT and E...
ORGANISM(S): Homo sapiens (Human) 
2017-01-30 | PXD004816 | Pride
Human Cfu-e Proteome ruler Label-free quantification 
MetabolomicsCXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury
Kidney injury is a common complication of severe disease. Here, we report that injuries of the zebrafish embryonal kidney are rapidly repaired by a migratory response in 2-, but not in 1-day-old embryos. Gene expression profiles between these two developmental stages identify cxcl12a and myca as can...
2018-10-11 | MTBLS723 | MetaboLights
ProteomicsProteome of BaF3-mEpoR cells stimulated with 5 U/ml Epo, 10 ng/ml IL-3 or left untreated
The proteome of BaF3-mEpoR cells stimulated with 5 U/ml Epo, 10 ng/ml IL-3 or left untreated were analyzed by label free LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-28 | PXD035181 | Pride
Baf3 Interleukin-3 Mouse Erythropoietin 
UnknownDNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells.
Not available
S-EPMC11460711 | biostudies-literature
UnknownHLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products.
Not available
S-EPMC11259936 | biostudies-literature
UnknownStructural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein.
Not available
S-EPMC7261188 | biostudies-literature
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