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UnknownQing-Kai-Ling oral liquid alleviates non-alcoholic fatty liver disease via remodeling gut microbiota and activating AMPK/ACC1 axis.
Not available
S-EPMC12536533 | biostudies-literature
ProteomicsHuman Mitochondria NFS1-ISCU-FXN XL-MS
Frataxin (FXN) is involved in mitochondrial iron-sulfur (Fe-S) cluster biogenesis and serves to accelerate Fe-S cluster formation. FXN deficiency is associated with Friedreich ataxia, a neurodegenerative disease. Using chemical cross-linking (XL) accompanied with LC-MS/MS, we studied the the interac...
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD006938 | Pride
Mitochondria Iron-sulfur cluster Xl-ms 
ProteomicsHuman Mitochondrial NFS1-FXN XL LS-MS/MS
Frataxin (FXN) is involved in mitochondrial iron-sulfur (Fe-S) cluster biogenesis and serves to accelerate Fe-S cluster formation. FXN deficiency is associated with Friedreich ataxia, a neurodegenerative disease. Using chemical cross-linking (XL) accompanied with LC-MS/MS, we studied the the interac...
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD006928 | Pride
Mitochondria Iron-sulfur cluster Xl Lc-ms/ms 
ProteomicsHuman mitochondrial cysteine desulfurase complex
Cysteine desulfurase plays central role in mitochondrial iron-sulfur cluster biogenesis not only by providing sulfur through the catalysis of L-cysteine to L-alanine but also by serving as the platform for the assembly of other components of the biosynthetic machinery, including ISCU, frataxin, and ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD009079 | Pride
Human Cysteine desulfurase Cx-ms 
TranscriptomicsRunx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells
The transcription factor RUNX1 is frequently mutated in myelodysplastic syndrome and leukemia. RUNX1 mutations can be early events, creating pre-leukemic stem cells that expand in the bone marrow. Here we show that, counter-intuitively, Runx1 deficient hematopoietic stem and progenitor cells (HSPCs)...
ORGANISM(S): Mus musculus 
2015-07-27 | E-GEOD-67609 | biostudies-arrayexpress
ProteomicsPlant pathogenic fungi influenced by citric acid
proteomics investigation about the impact of micromolar citric acid on Fusarium graminearum
ORGANISM(S): Fusarium Graminearum Ph-1 
2024-07-03 | PXD053628 |
UnknownJasmonic acid regulates the biosynthesis of medicinal metabolites via the JAZ9-MYB76 complex in Salvia miltiorrhiza.
Not available
S-EPMC10022484 | biostudies-literature
UnknownGeneration of tooth-like structures from integration-free human urine induced pluripotent stem cells.
Not available
S-EPMC4230506 | biostudies-literature
UnknownHuman Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus.
Not available
S-EPMC7940440 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
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