Cai L L - OmicsDI

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Unknown (13983)
Proteomics (314)
Transcriptomics (213)
Metabolomics (108)
Genomics (32)
Models (1)
Other (1)

Organisms

Homo sapiens (277)
Mus musculus (102)
Saccharomyces cerevisiae (16)
Arabidopsis thaliana (15)
Brassica rapa subsp. pekinensis (7)
Rattus norvegicus (7)
Oryza sativa (6)
Drosophila melanogaster (4)
Haloarcula hispanica (3)
Brassica napus (3)
Sus scrofa (3)
Rattus rattus (2)
Neurospora crassa OR74A (2)
Myzus persicae (2)
Glycine soja (2)
Dictyostelium discoideum (2)
Brassica rapa (2)
Triticum aestivum (2)
Pseudoalteromonas sp. SM9913 (1)
Brassica rapa subsp. oleifera (1)
Lasioglossum albipes (1)
Oryza rufipogon (1)
Haloferax mediterranei (1)
Lactobacillus helveticus (1)
Schistosoma japonicum (1)
Clostridium botulinum (1)
uncultured bacterium (1)
Brassica rapa subsp. chinensis (1)
Mytilus edulis (1)
Bombyx mori (1)

Repository

biostudies-arrayexpress (238)
pride (152)
MetaboLights (103)
iProX (83)
PeptideAtlas (63)
MassIVE (12)
EGA (8)
MetabolomicsWorkbench (3)
GNPS (2)
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GPMDB (1)
jPOST (1)
PAXDB (1)
ENA (1)

Tissue

Liver (44)
Cell culture (29)
Epithelial cell (13)
Whole body (8)
Blood plasma (6)
Blood serum (6)
Brain (6)
Liver (6)
Leaf (5)
Blood cell (4)
Hepatocyte (4)
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Stem cell (4)
Thyroid nodule (4)
Others (3)
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Cells (1)
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Lung (1)

Disease

Breast cancer (6)
Cancer (2)
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Friedreich ataxia (2)
Hepatocellular carcinoma (2)
Mixed disorder as reaction to stress (2)
Salmonella gastroenteritis (2)
Uveal melanoma (2)
Not Available (1)
Alzheimer's disease (1)
Avian influenza (1)
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Endometrial cancer (1)
Low grade glioma (1)
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Lung cancer (1)
Lymphoma (1)
Malaria (1)
Malignant neoplasm of ovary (1)
Medullary thyroid carcinoma (1)
Melanoma (1)
Myeloproliferative neoplasm (1)
Neurilemmomatosis (1)
Noonan syndrome (1)
Prostate adenocarcinoma (1)
Thyroid cancer (1)

Technology Type

Mass Spectrometry (155)
Mass spectrometry (80)
Shotgun proteomics (75)
Bottom-up proteomics (23)
Mass spectrometry assay (22)
Data-dependent acquisition (17)
Gel-based experiment (11)
Affinity purification coupled with mass spectrometry proteomics (10)
SWATH MS (9)
Chemical cross-linking coupled with mass spectrometry proteomics (6)
Data-independent acquisition (6)
ESI (3)
DiaPASEF (3)
SRM/MRM (2)
Top-down proteomics (2)
ION_TORRENT, Ion Torrent Proton (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
All-ion fragmentation (1)
HDMSE (1)
MSE (1)
Proteogenomics (1)

Instrument Platform

Illumina NovaSeq 6000 (5)
Q Exactive HF (3)
Orbitrap Exploris 480 (3)
Illumina HiSeq 2000 (2)
TripleTOF 6600 (2)
Linux Bash Scripting (1)
NEBNext Ultra II Directional RNA Library Prep (1)
Qiagen RNeasy Mini Kit (1)
With L-glutamine supplemented with 10% fetal bovine serum (FBS) (Gibco) and 1% penicillin-streptomycin (10,000 units/mL penicillin and 10 mg/mL streptomycin) (Gibco). (1)
Aspara® Smart Grower Hydroponic (1)
GeneChip® Fluidics Station 450 and GeneChip® Scanner 3000 (1)
Affymetrix 3'IVT Express Kit (1)
Agilent 2100 Bioanalyzer (1)
Scanning hardware (1)
R (1)
10X Chromium (1)
NovaSeq PE150 (1)
Spectrum™ Plant Total RNA Kit (1)
Illumina MiSeq (1)
NextSeq 550 (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Instrument (1)
AB Sciex QTRAP 6500 (1)
MaXis (1)
Orbitrap Eclipse (1)
Q Exactive (1)
Q Exactive mass spectrometer (Thermo Scientific) (1)
Thermo EASY-nLC 1200 (1)

Publication Date

2025 (64)
2022 (61)
2023 (47)
2013 (47)
2024 (44)
2020 (40)
2021 (38)
2026 (34)
2014 (31)
2015 (30)
2012 (29)
2016 (27)
2010 (24)
2011 (17)
2019 (15)
2008 (13)
2018 (12)
2009 (7)
2017 (6)
2006 (5)
2004 (4)
2007 (3)
2005 (1)
2002 (1)
2001 (1)

UNIPROT ID/AC

1FEH1_WHEAT (1)
4565.EPlTAEP00000010002 (1)
4565.EPlTAEP00000010027 (1)
4565.EPlTAEP00000010105 (1)
4565.EPlTAEP00000010109 (1)
4565.EPlTAEP00000010115 (1)
4565.Traes_1AL_00485097A.2 (1)
4565.Traes_1AL_00744EBC6.2 (1)
4565.Traes_1AL_0121566F8.1 (1)
4565.Traes_1AL_013C8AF6B1.1 (1)
4565.Traes_1AL_014F29DA6.1 (1)
4565.Traes_1AL_015BAE72C.1 (1)
4565.Traes_1AL_01806281A.1 (1)
4565.Traes_1AL_0226AAD07.1 (1)
4565.Traes_1AL_034B63223.1 (1)
4565.Traes_1AL_036E330F0.1 (1)
4565.Traes_1AL_03D275069.1 (1)
4565.Traes_1AL_0458C8353.1 (1)
4565.Traes_1AL_04A4521BB.2 (1)
4565.Traes_1AL_04EA15F57.1 (1)
4565.Traes_1AL_051FE2815.1 (1)
4565.Traes_1AL_087978D78.1 (1)
4565.Traes_1AL_08A2F5FA4.1 (1)
4565.Traes_1AL_08A7811E1.3 (1)
4565.Traes_1AL_0912DED70.1 (1)
4565.Traes_1AL_093513BF1.1 (1)
4565.Traes_1AL_09486AD47.1 (1)
4565.Traes_1AL_0A1043127.1 (1)
4565.Traes_1AL_0A5A0E0D3.1 (1)
4565.Traes_1AL_0A7711D82.1 (1)

ENSEMBL ID

ENSG00000170477 (4)

CHEBI ID

CHEBI:15891 (29)
CHEBI:17368 (28)
CHEBI:16919 (24)
CHEBI:17750 (24)
CHEBI:30769 (24)
CHEBI:16335 (23)
CHEBI:16704 (23)
CHEBI:16708 (23)
CHEBI:16750 (23)
CHEBI:17895 (23)
CHEBI:16467 (22)
CHEBI:16828 (22)
CHEBI:17596 (22)
CHEBI:18183 (22)
CHEBI:16015 (21)
CHEBI:16737 (21)
CHEBI:17015 (21)
CHEBI:17568 (21)
CHEBI:15428 (20)
CHEBI:17295 (20)
CHEBI:15971 (19)
CHEBI:16235 (19)
CHEBI:17154 (19)
CHEBI:17351 (19)
CHEBI:18132 (19)
CHEBI:28044 (19)
CHEBI:15756 (18)
CHEBI:16040 (18)
CHEBI:16595 (1)
CHEBI:29108 (1)

Metabolite Name

Hypoxanthine (30)
Adenine (28)
Adenosine (25)
Uracil (25)
Uridine (25)
Guanosine (24)
Taurine (24)
Betaine (22)
Creatine (22)
Cytosine (20)
Inosine (20)
Creatinine (19)
Cytidine (18)
Histamine (18)
Riboflavin (18)
Xanthosine (18)
L-Glutamine (17)
Palmitic acid (17)
Xanthine (17)
Deoxyinosine (16)
Guanine (16)
L-Arginine (16)
L-Phenylalanine (16)
L-Tyrosine (16)
N-Acetylputrescine (16)
Choline (15)
Citrulline (15)
Glycerophosphocholine (15)
Oleamide (15)
1-Methyladenosine (14)

IsPrivate

False (1)

First Public Date

2018 (1)

Modelling Approach

Ordinary differential equation model (1)

Modification

0.9840160012245178 (1)
15.994915 (1)
15.994915008544922 (1)
42.010565 (1)
57.021464 (1)
57.02146530151367 (1)
Not available (1)

Study type

Transcription profiling by array (131)
RNA-seq of coding RNA (47)
ChIP-seq (17)
RNA-seq of non coding RNA (12)
Methylation profiling by high throughput sequencing (6)
Comparative genomic hybridization by array (5)
Unknown experiment type (3)
Other (3)
RNA-seq of coding RNA from single cells (3)
Genotyping by array (2)
Proteomic profiling by array (2)
Transcription profiling by SAGE (1)
ChIP-chip by tiling array (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Transcription profiling by RT-PCR (1)
Methylation profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2025 (2160)
2022 (1937)
2023 (1700)
2024 (1694)
2021 (1439)
2020 (1092)
2019 (751)
2018 (641)
2017 (581)
2016 (494)
2015 (401)
2026 (320)
2014 (307)
2013 (235)
2012 (148)
2011 (90)
2010 (89)
2009 (48)
2008 (39)
2007 (15)
2006 (15)
2004 (8)
2005 (5)
2002 (5)
2003 (4)
2001 (2)
1997 (1)

Lab affiliation

Univeristy of Georgia (5)
Institute of Biophysics, Chinese Academy of Sciences (4)
Shenzhen People’s Hospital (3)
Zhejiang University (3)
Department of Biochemistry University of Wisconsin-Madison (2)
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, 75390, TX, USA (2)
Department of Biological Sciences, Purdue University (2)
Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, China (2)
Department of Cell and Molecular Biology, College of Medicine, Chang Gung University, Taoyuan, Taiwan (2)
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China. (2)
Jiangsu Academy of Agricultural Sciences (2)
The First Affiliated Hospital of Zhejiang University School of Medicine (2)
University of Science and Technology of China (2)
University of Wisconsin-Madison (2)
hong kong baptist university (2)
1 Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, PR China 2 Department of Microbiology and Immunology, Tongji University School of Medicine, Shanghai 200049, PR China 3 Clinical Translation Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China. (1)
1.Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2.Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China 3.Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases, Shanghai, China (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA 3Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 3Biological and Biomedical Sciences Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 5Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 8Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA (1)
Aarhus University, Department of Molecular Biology and Genetics (1)
Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine (1)
Assistant Professor, Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center (1)
Associate Professor Developmental and Regenerative Biology School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong (1)
BCI Mass spectrometry Facility 1.02 & 1.03 1st floor Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ (1)
Baxter Laboratory for Stem Cell Biology Department of Microbiology & Immunology Stanford University School of Medicine 269 Campus Drive CCSR 3205b Stanford, CA 94305-5175, USA (1)
Beijing University of Agriculture, China (1)
Biochemistry and Molecular Genetics, Hematology and Oncology, Department of Medicine, Northwestern University, USA (1)
Biological NMR and HDX-MS Platform, Institut Pasteur, Université Paris Cité, CNRS UMR 3528, 75015 Paris, France (1)
Bone Marrow Transplantation Center, Department of Hematology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China (1)

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Methionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma

Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...

2026-06-09 | MTBLS11985 | MetaboLights

Target of L-menthol in keratinocytes

To elucidate the PP6-upregulation mechanism of L-menthol, we took advantage of an unbiased target identification approach, DARTS, to identify the target of L-menthol in keratinocytes.

ORGANISM(S): Homo sapiens (Human)

2022-11-09 | PXD037335 | Pride

Keratinocyte，hes1 L-menthol

irs4 versus CAI-12

Comparison of expression profiling of irs4 null mutant versus isogenic strain (CAI-12) grown in blood (3 replicates) Two-condition experiment, irs4 null mutant versus CAI-12 wild-type. Biological replicates: 3 irs4 null mutant, 3 wild-type. Two replicates per array.

ORGANISM(S): Candida albicans

2012-10-06 | E-GEOD-41330 | biostudies-arrayexpress

Metabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress

Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...

2018-07-27 | MTBLS481 | MetaboLights

Cai xin, lettuce and spinach gene expression atlas

Raw RNAseq data of hydroponically grown crops (cai xin, lettuce, and spinach) subjected under 31 different conditions. Comparative analysis of gene expression across species and stress conditions were carried out.

ORGANISM(S): Brassica rapa

2024-04-30 | E-MTAB-14018 | biostudies-arrayexpress

A genomic approach to bud mutation in sweet orange (Citrus sinensis L. Osbeck) fruit

Bud mutations arise often in citrus. The selection of mutants is one of the most important breeding methods in citrus. However, the molecular bases of bud mutation have rarely been studied. To identify the potential important or novel genes involved in bud mutation, different transcriptomic techniqu...

ORGANISM(S): Citrus sinensis

2009-03-09 | E-GEOD-10729 | biostudies-arrayexpress

Adipose mitochondrial functional enhancement via DsbA-L rewires systemic aging through an adipokine-mediated longevity pathway

Mitochondrial dysfunction is a hallmark of aging, but whether restoring mitochondrial function in adipose tissue alone can delay systemic aging is unknown. Here we show that adipose-specific upregulation of the mitochondrial chaperone DsbA-L in mice improves metabolic and cognitive function and exte...

ORGANISM(S): Mus musculus (Mouse)

2026-10-27 | PXD086072 | Pride

Adipokines Adipose tissue Healthy ageing Mitochondrial function Berberine

Threonine dehydratase couples L-cysteine metabolism to cadmium resistance in Pseudomonas stutzeri 273 through cadmium sulfide nanoparticle biomineralization

Cysteine is an amino acid containing sulfhydryl (-SH) group which is the basis of cysteine involved in sulfur metabolism and heavy metal detoxification in microorganisms. Here, we demonstrate that adding L-cysteine significantly improves the cadmium resistance and removal ability of Pseudomonas stut...

ORGANISM(S): Pseudomonas stutzeri (Pseudomonas perfectomarina)

2022-03-01 | PXD011469 | Pride

Pseudomonas stutzeri 273 Qrt-pcr Mutants

PP6 interated proteins in HaCaT cells treated with L-menthol

Because HES1 maintained PP6 protein level without affecting its mRNA level, we asked if HES1 directly interacted with PP6 in keratinocytes.