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ProteomicsAssociating H2O2 and NO related changes in the proteome of Mycobacterium smegmatis with enhanced survival in macrophages
In this study, we used mass spectrometry-based discovery proteomic analysis to examine the cell-wide changes of Mycobacterium smegmatis, in response to sub-lethal concentrations of H2O2 and nitric oxide (NO) over time. Preliminary results have shown that sub-lethal concentrations of reactive oxyge...
ORGANISM(S): Mycobacterium smegmatis 
2019-11-12 | PXD010020 | Pride
No Sub-lethal concentrations Signalling Ros H2o2 Mycobacterium Proteomics 
ProteomicsQuantitative label-free proteomic analysis of human urine to identify novel protein biomarkers for schistosomiasis
Background: Schistosomiasis is a chronic neglected tropical disease that is characterized by continued inflammatory challenges to the exposed population, and it has been established as a possible risk factor in the aetiology of bladder cancer. Improved diagnosis of schistosomiasis and its associated...
ORGANISM(S): Homo sapiens (Human) Schistosoma haematobium 
2017-10-24 | PXD006438 | Pride
Schistosoma haematobium Bladder cancer Discovery proteomics Qexactive Schistosomiasis Biomarkers 
ProteomicsIdentification of quantitative proteomic differences between mycobacterial lineages with altered virulence
Mycobacterium tuberculosis is the causitive agent of TB, which is a global epidemic that has claimed millions of lives. Some clinical strains of M.tb have significantly more severe clinical outcomes, while some other mycobacteria ordinarily do not cause disease in humans. The biological processes un...
ORGANISM(S): Mycobacterium tuberculosis str. Beijing/W BT1 Mycobacterium tuberculosis H37Rv Mycobacterium avium 100 Mycobacterium tuberculosis CAS Mycobacterium bovis BCG Mycobacterium bovis str. Ravenel Mycobacterium tuberculosis LAM7 
2016-05-23 | PXD004165 | Pride
Srm Virulence Discovery Mycobacteria Pathogenicity 
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