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Cxcl14+/- mice were mated with Cxcl14+/- mice, the embryos of pregnant females were collected on E13.5. After genotyping, the maternal part and fetal part of Cxcl14-/- and Cxcl14+/+ placentas were dissect out to extract total RNA respectively (n = 3). Total RNA was extracted using PureYield™ RNA Mid...
ORGANISM(S): Mus musculus 
Atherosclerosis arises from disrupted cholesterol metabolism, notably impaired macrophage cholesterol efflux leading to foam cell formation. Through single-cell and bulk RNA sequencing, we identified Listerin as a regulator of macrophage cholesterol metabolism. Listerin expression increased during a...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-11 | PXD064538 | Pride
Atherosclerosis arises from disrupted cholesterol metabolism, notably impaired macrophage cholesterol efflux leading to foam cell formation. Through single-cell and bulk RNA sequencing, we identified Listerin as a regulator of macrophage cholesterol metabolism. Listerin expression increased during a...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-11 | PXD064532 | Pride
Chromatin insulators organize the genome into distinct transcriptional domains and contribute to cell type-specific chromatin organization. However, factors regulating tissue-specific insulator function have not yet been discovered. Here we identify the RNA recognition motif-containing protein, Shep...
ORGANISM(S): Drosophila melanogaster 
Lei et al. screen out Lactococcus lactis OMVs (Lac-OMVs) and develop metabolic-engineered NAD+-Lac-OMVs nanovaccine with potent tissue repair therapeutic effect. NAD+-Lac-OMVs sequentially activate dendritic cells by membrane component and reprogram inflammatory macrophages for anti-inflammation and...
ORGANISM(S): Mus Musculus 
2026-03-23 | PXD076052 |
Chromatin insulators are functionally conserved DNA-protein complexes that are situated throughout the genome and organize independent transcriptional domains.  Previous work implicated RNA as an important cofactor in chromatin insulator activity, although the mechanisms by which RNA affects insulat...
ORGANISM(S): Drosophila melanogaster 
Background: Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and physical outcomes in the offspring. Although epigenetic processes may be responsible for PNMS effects, human research is hampered by the lack of experimental methods that parallel controlled animal studies. Disaste...
ORGANISM(S): Homo sapiens 
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