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Recent evidence that the unicellular ancestor of animals had a complex repertoire of genes linked to multicellular processes suggests that changes in the regulatory genome, rather than gene innovation, were key to the origin of animals. Here, we carry out multiple functional genomic assays in Capsas...
ORGANISM(S): Capsaspora owczarzaki 
2018-10-24 | PXD002342 | Pride
The dynamic regulatory genome of Capsaspora owczarzaki and the origin of animal multicellularity
Capsaspora genome assembly improvement
Nanopore sequencing of Capsaspora
We carried out multiple functional genomic assays in Capsaspora owczarzaki, the unicellular relative of animals with the largest known gene repertoire for transcriptional regulation. We show that changing chromatin states, differential lincRNA expression and dynamic cis-regulatory sites are associat...
ORGANISM(S): Capsaspora owczarzaki 
2016-04-12 | GSE71131 | GEO
Cell-specific regulation of protein levels and activity is essential for the distribution of functions among multiple cell types in animals. The finding that many genes involved in these regulatory processes have a premetazoan origin raises the intriguing possibility that the mechanisms required for...
ORGANISM(S): Capsaspora owczarzaki 
2016-11-30 | PXD004567 | Pride
An amoeboid symbiont of a pulmonate snail
An amoeboid symbiont of a pulmonate snail
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