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Simultaneous Membrane and RNA Binding by Tick-Borne Encephalitis Virus Capsid Protein

Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the endoplasmic reticulum membrane and acquires ...

2023-01-06 | MTBLS6076 | MetaboLights

Expression data from the hepatitis E virus capsid protein

The hepatitis E virus (HEV), a non enveloped RNA virus, causes viral hepatitis. The viral open reading frame 2 (ORF2) protein represents the capsid protein of HEV which is known to cause endoplasmic reticulum stress in ORF2 expressing cells. The initiation of endoplasmic reticulum stress induced apo...

ORGANISM(S): Homo sapiens

2012-12-01 | E-GEOD-29061 | biostudies-arrayexpress

Sequencing of Echinococcus multilocularis densovirus non capsid protein 1 gene

PRJEB29456 | ENA

Cellular proteins interacting with curved HIV-1 capsid lattices

Early events of HIV-1 lifecycle, such as post-entry virus trafficking, uncoating and nuclear import, remain poorly understood due to limited information about virus-host interactions. We used a multidisciplinary approach. First, a mass spectrometry (MS)-based proteomics methodology enabled us to ide...

ORGANISM(S): Homo sapiens (Human)

2021-01-04 | PXD020970 | Pride

Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction

Here, we present our investigation of the viral proteins of the capsid of adeno-associated viruses via top-down mass spectrometry on the LC timescale. Characterization was improved through the use of proton transfer charge reduction

ORGANISM(S): Human Aav

2024-06-14 | MSV000095045 | MassIVE

Degraders of the dengue virus capsid protein exhibit differentiated pharmacology relative to capsid inhibitors

Due to the limited size of viral genomes, most viral proteins are multifunctional; yet most direct-acting antivirals are designed as single-function inhibitors. The dengue virus (DENV) capsid protein serves as a building block for new virions while also interacting with multiple host factors to remo...

ORGANISM(S): Homo sapiens (Human)

2026-03-30 | PXD063557 | Pride

Degrader Dengue Capsin Virus Crbn Chemical biology Protac Ubiquitin

Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants

PRJNA389816 | ENA

PAR-CLIP Semliki Forest virus capsid protein

PRJNA657426 | ENA

Characterisation of the Semliki Forest Virus-host cell interactome reveals the viral capsid protein as an inhibitor of nonsense-mediated mRNA decay

Understanding the complex interactions between the viral and the host cell proteins is crucial for elucidating the mechanisms underlying successful virus replication strategies and for developing specific antiviral interventions. This project presents the first comprehensive protein-protein interact...

ORGANISM(S): Homo sapiens (Human) Semliki Forest virus

2021-05-07 | PXD022036 | Pride

Semliki forest virus sfv capsid sirna screen alphavirus rna virus nmd virus-host protein interactions Nonsense-mediated mrna decay

Expression data from transgenic Nicotiana tabacum expressing a variant of coat protein and movement protein from Tobacco mosaic virus

Transgenic expression of viral proteins in natural host plants is a useful simplified system with the potential to understand the individual effect of each viral component. Transgenic expression of movement (MP) and a variant from coat protein (CPT42W) in tobacco, a TMV natural host, produces sever...

ORGANISM(S): Nicotiana tabacum

2012-12-01 | E-GEOD-37905 | biostudies-arrayexpress

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