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Carbon dioxide regulates cellular processes as diverse as metabolism, cellular homeostasis, chemosensing and pathogenesis. CO2 is generally unreactive but can interact with neutral amines on protein under normal introcellular conditions to form a carbamate post-translational modification. This data ...
ORGANISM(S): Escherichia coli 
2022-05-19 | PXD019606 | Pride
Cross-linking mass spectrometry (XL-MS) has become a valuable tool for investigating the structural morphology and plasticity of proteins. Traditional cross-linkers contain two N-hydroxy succinimide (NHS) esters that mainly react with lysine residues. In this work, we optimized the in-solution react...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2026-03-30 | PXD069252 | Pride
microRNA expression in lung tumors of viny-carbamate treated and viny-carbamate and indole-3-carbinol treated mice
Chemical cross-linking/mass spectrometry (XL-MS) has emerged as a complementary tool for mapping interaction sites within protein networks as well as gaining moderate-resolution native structurale insight with minimal interference. XL-MS technology mostly relies on chemoselective reactions (crosslin...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051742 | Pride
Excess/residual urea is a pervasion problem in wine and Sake fermentation. We sought to reduce residual urea levels (to reduce ethyl carbamate leves) by engineering the Sake yeast strain K7 to constitutively express either the urea amidolyase (Dur1,2) or urea importer (Dur3). We sought to then compa...
ORGANISM(S): Saccharomyces cerevisiae 
Effects of ethyl carbamate exposure on C. elegans transcriptome
Ethyl carbamate is a common food contaminant prevalent in fermented food with probable carcinogenic effects in animals. To date, other toxicological properties of ethyl carbamate are not well characterized. Using the genetic model Caenorhabditis elegans, we found that chronic exposure to ethyl carba...
ORGANISM(S): Caenorhabditis elegans 
2022-04-13 | GSE190099 | GEO
We examined the differential expression of miRNAs in vinyl carbamate (VC)-induced lung tumors in A/J mice and assessed if the chemopreventive agent indole-3-carbinol (I3C) reversed the effects of the carcinogen. Microarray studies revealed some up-regulated microRNAs, but down-regulation of several ...
ORGANISM(S): Mus musculus 
We examined the differential expression of miRNAs in vinyl carbamate (VC)-induced lung tumors in A/J mice and assessed if the chemopreventive agent indole-3-carbinol (I3C) reversed the effects of the carcinogen. Microarray studies revealed some up-regulated microRNAs, but down-regulation of several ...
ORGANISM(S): Mus musculus Danio rerio Homo sapiens Caenorhabditis elegans Drosophila melanogaster Rattus norvegicus 
2009-12-06 | GSE16490 | GEO
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