Sort   by:  
 Page size 
ProteomicsBiliary Tract Carcinogenesis Model Based on Bile Metaproteomics
Purpose: To analyze human and bacteria proteomic profiles in bile, exposed to a tumor vs. non-tumor microenvironment, in order to identify differences between these conditions, which may contribute to a better understanding of pancreatic carcinogenesis. Patients and Methods: Using liquid chromatogr...
ORGANISM(S): Homo sapiens (Human) 
2020-07-08 | PXD020151 | Pride
Zeatin Bile Pancreatic cancer Carcinogenesis model Proteomic Il-8 Metaproteomic Surfactin 
ProteomicsOrganoid-trasplant model systems to study in vivo the effects of obesity on the pancreatic carcinogenesis
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality among adults in developed countries. The discovery of the most common genetic alterations as well as the development of organoids models of pancreatic cancer have provided insight into the fundamental path...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD018362 | Pride
Carcinogenesis Obesity Organoid models Adipokines Pancreatic cancer 
ProteomicsTracking prostate carcinogenesis over time through urine proteome profiling in an animal model: an exploratory approach
The urgent need for new tools for the early diagnosis of prostate cancer (PCa) has prompted us to investigate the proteomic profile of urine during the course of prostate carcinogenesis. Using an established animal model of prostate adenocarcinoma, we performed a comprehensive analysis of the proteo...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-08-12 | PXD034432 | Pride
Prostate adenocarcinoma Cadherin-2 Urinary proteomics Aging Gelc-ms/ms Enolase-1 Retinol-binding protein 4 
ProteomicsLoss of colonic primary cilia promotes inflammation and carcinogenesis
Primary cilia (PC) are important signaling hubs in cells and we explored their role in colorectal cancer (CRC) and colitis. In the colon we found PC to be mostly present on different subtypes of fibroblasts and exposure of mice to either chemically induced colitis-associated colon carcinogenesis (CA...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-29 | PXD033440 | Pride
Colon carcinogenesis Inflammation Primary cilia Colonic fibroblasts Colitis 
TranscriptomicsHematopoietic cells-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury
Chronic liver injury triggers complications such as liver fibrosis and hepatocellular carcinoma (HCC), which are associated with alterations in distinct signaling pathways. Of particular interest is the interaction between mechanisms controlled by IKKγ/NEMO, the regulatory IKK subunit, and Jnk activ...
ORGANISM(S): Mus musculus 
2015-06-22 | E-GEOD-59601 | biostudies-arrayexpress
UnknownProtective role of cathepsin L in mouse skin carcinogenesis.
Not available
S-EPMC3155742 | biostudies-literature
GenomicsCirculating miRNA profile of MMTV-NeuT mouse model of spontaneous mammary carcinogenesis.
Circulating miRNA profile of MMTV-NeuT mouse model of spontaneous mammary carcinogenesis.
PRJNA480862 | ENA
TranscriptomicsMicroarray analysis of rat mammary carcinogenesis
7,12-Dimethylbenz[a]anthracene (DMBA)-induced rat mammary carcinoma is a well-recognized model, however, the genetic alterations during its carcinogenesis have yet to be determined. We used laser capture microdissection to specifically isolate cells from terminal end buds (TEBs), the origin of carci...
ORGANISM(S): Rattus norvegicus 
2008-10-28 | E-GEOD-13356 | biostudies-arrayexpress
UnknownUse of a TGFbeta type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFbeta signaling in tumor promotion and progression.
Not available
S-EPMC2994279 | biostudies-literature
TranscriptomicsTranscriptomic analysis of TLR4 pathways in a murine model of chronic pulmonary inflammation and carcinogenesis
Toll like receptor 4 (TLR4), an innate immunity gene, is involved in responses to several pulmonary agonists including endotoxin (LPS; Poltorak et al.,1998), ozone (O3 ,Kleeberger et. al., 2001), Pseudomonas aeruginosa (Faure et al, 2004), and hyperoxia (Zhang et al, 2005). TLR4 appears to partially...
ORGANISM(S): Mus musculus 
2009-12-12 | E-GEOD-8504 | biostudies-arrayexpress
Sort   by:  
 Page size