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ProteomicsThe anti-MRSA compound KCR inhibits protein synthesis in Staphylococcus aureus
S aureus was treated in triplicate with 3-O-alpha-L-(2",3"-di-p-coumaroyl)rhamnoside (KCR), oxacillin or vehicle and quantitative proteomic analysis was carried out using isobaric tags and mass spectrometry. 1190 proteins were identified and 552 were affected by KCR (q<0.01). Ontology analysis ide...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
MSV000084282 | MassIVE
ProteomicsMercury Uniquely Alters B-Cell Protein Phosphorylation Profiles
To test the hypothesis that HgCl2 acts as a phospho-tyrosine phosphatase inhibitor in B-cells, we treated the WEHI-231 cell line for 10 min with HgCl2 at 100 uM or 250 uM, okadaic acid at 100 nM or pervanadate at 25 uM and analyzed the phosphoproteome by TiO2 affinity chromatography and LC-MS/MS. ...
ORGANISM(S): Mus musculus (Mouse) 
2013-12-10 | PXD000312 | Pride
Phosphoprotein B-cell Mercury Phosphoylation Pervanadate Hg 
UnknownThe anti-MRSA compound 3-O-alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR) inhibits protein synthesis in Staphylococcus aureus.
Not available
S-EPMC7014561 | biostudies-literature
TranscriptomicsTranscriptome analysis of Escherichia coli O157:H7 EDL933 during anaerobic growth using microarrays
The transcriptome of Escherichia coli K-12 has been widely studied over a variety of conditions for the past decade while such studies involving E. coli O157:H7, its pathogenic cousin, are just now being conducted. To better understand the impact of an anaerobic environment on E. coli O157:H7, globa...
ORGANISM(S): Escherichia coli 
2010-12-01 | E-GEOD-13301 | biostudies-arrayexpress
UnknownChronic Low Dose Oral Exposure to Microcystin-LR Exacerbates Hepatic Injury in a Murine Model of Non-Alcoholic Fatty Liver Disease.
Not available
S-EPMC6783870 | biostudies-literature
ProteomicsSingle amino acid variant
We performed deep proteomic profiling down to as few as 9 Panc-1 cells using sample fractionation, TMT multiplexing and carrier/reference strategy. Off line fractionation of the TMT-labeled sample pooled with TMT-labeled carrier Panc-1 whole cell proteome was achieved using alkaline reversed phase s...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD011471 | Pride
Human Panc-1 Lc-ms/ms 
ProteomicsThe human diabetes-specific visceral adipose tissue proteome: insights into mechanisms of adipose tissue dysfunction in metabolic disease
Introduction: The human adipose tissue proteome associated with type 2 diabetes (DM) is not well described. An understanding of the DM-specific adipose tissue proteome would provide insight into mechanisms underlying the pathogenesis of DM. Methods: We used label-free proteomics analysis to quanti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-27 | MSV000085169 | MassIVE
UnknownThe TGF-β inhibitory activity of antibody 37E1B5 depends on its H-CDR2 glycan.
Not available
S-EPMC5240645 | biostudies-literature
UnknownA Comprehensive Phylogenomic Platform for Exploring the Angiosperm Tree of Life.
Not available
S-EPMC8830076 | biostudies-literature
UnknownHigh-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
Not available
S-EPMC3605761 | biostudies-literature
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