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ProteomicsCombined cysteine oxidation (C6-CPT/CysPAT) proteomics and phosphoproteomics of pervanadate-treated of HEK293T cells
HEK293T cells were treated with pervanadate for 0, 5 or 15 minutes to evaluate the effects on the phosphorylation and cysteine oxidation status across the proteome. Samples were labelled withTMT 18plex and C6-CPT/CysPAT labelling was used to allow the simultaneous enrichment of both the phosphoprote...
ORGANISM(S): Homo sapiens (Human) 
2026-06-22 | PXD059503 | Pride
Hek293t Cysteine C6-cyspat C6-cpt Redox Phosphoproteomics Pervanadate 
UnknownPervanadate stabilizes desmosomes.
Not available
S-EPMC2634090 | biostudies-literature
ProteomicsTandem Mass Tag approach utilizing pervanadate BOOST channels delivers deeper quantitative characterization of the tyrosine phosphoproteome
Dynamic tyrosine phosphorylation is fundamental to a myriad of cellular processes. However, the inherently low abundance of tyrosine phosphorylation in the proteome and the inefficient enrichment of phosphotyrosine(pTyr)-containing peptides has led to poor pTyr peptide identification and quantitati...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD016192 | Pride
Superbinder Trigger channel Phosphotyrosine proteomics Tandem mass tags Pervanadate 
ProteomicsPervanadate reveals a new redox model of cellular phosphotyrosine 1 signaling C4PR_LIV
Protein tyrosine phosphorylation (pTyr) is controlled by protein tyrosine kinases and phosphatases (PTPs) and allows cells to sense and respond to changes in their environment. Pervanadate is a widely used chemical tool that induces global pTyr, a phenomenon attributed to its properties as a PTP inh...
ORGANISM(S): Homo sapiens (Human) 
2026-03-10 | PXD059641 | Pride
OtherProteomic analysis of pervanadate-induced tyrosine-phosphorylated proteins in hepatocellular carcinoma WRL 68 cells
Proteomic analysis of pervanadate-induced tyrosine-phosphorylated proteins in hepatocellular carcinoma WRL 68 cells Protein tyrosine phosphorylation plays critical roles in modulating biological processes such as cellular proliferation, differentiation, migration, apoptosis and metabolism. To profil...
ORGANISM(S): Homo sapiens 
2005-04-07 | GSE2408 | GEO
ProteomicsPervanadate mediated cysteine oxidation directly activates SRC kinase
Protein tyrosine phosphorylation (pTyr) is regulated by protein tyrosine phosphatases (PTPs) and27 kinases, helping cells detect and react to environmental changes. Pervanadate is commonly used to increase pTyr levels by inhibiting PTPs, leading to the belief that PTPs are the main regulators of pTy...
ORGANISM(S): Homo sapiens (Human) 
2026-02-05 | PXD059840 | Pride
Src Oxidation Kinase Hdx-ms 
ProteomicsAnalysis of CD5 signalosome in primary T cells
CD5 is characterized as an inhibitory co-receptor with important regulatory role during T cell development. To study the molecular mechanism by which CD5 operates, we used quantitative mass spectrometry to analyze the components of the CD5 signaling machinery in primary T cells. In a first set of ex...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-18 | PXD017343 | Pride
Tyrosine phosphorylation Cd5 Interactomics Tcr 
ProteomicsDanio rerio thermal proteome profiling with pervanadate as drug of interest
In this study we performed thermal proteome profiling experiments on zebrafish lysate after treatment with the drug pervanadate.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2020-10-29 | PXD017418 | Pride
High ph Tmt Danio rerio Thermal proteome profiling 
UnknownTandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome.
Not available
S-EPMC7124467 | biostudies-literature
ProteomicsSupplementary Dataset 11c - SILAC data for HEK293T-Subtiligase-Y217D-TM Pervanadate treated vs untreated
This dataset contains SILAC data for HEK293T-subtiligase-Y217D-TM cells, pervanadate treated vs. untreated. In Q20180422-04, light cells were pervanadate treated and heavy cells were the control. In Q20180422-08 and Q20180422-10, heavy cells were pervanadate treated and light cells were the control.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-21 | MSV000084995 | MassIVE
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