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UnknownPhysicians' moral distinctions between medical assistance in dying (MAiD) and withdrawing life-sustaining treatment in Canada: a qualitative descriptive study.
Not available
S-EPMC11786344 | biostudies-literature
TranscriptomicsTranscription profiling of human Hela cells infected with Vaccinia mutants
Samples were received from the lab of Bertram Jacobs, experiments done by Jeff Langland (langland@asu.edu). Midlog Hela cells were infected with copenhagen strain Vaccinia Virus at MOI of 5. Viral stocks were sucrose pad purified. Incubated 2, 6, and 9 hrs post infection. viral mutants include VC2 (...
ORGANISM(S): Homo sapiens 
2007-04-01 | E-TABM-64 | biostudies-arrayexpress
UnknownIntegrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.
Not available
S-EPMC4062710 | biostudies-literature
TranscriptomicsComparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains
Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of human...
ORGANISM(S): Clostridium botulinum 
2007-05-23 | E-TABM-264 | biostudies-arrayexpress
TranscriptomicsRegulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes
The juvenile onset of spermatogenesis in mice is analyzed by combining cytological and transcriptomic data in a novel computational analysis, resulting in meiotic substage-specific transcriptomes and the discovery of a transcription factor network that regulates the substages of meiosis. Germ cells ...
ORGANISM(S): Mus musculus 
2016-08-24 | E-GEOD-72833 | biostudies-arrayexpress
TranscriptomicsAn integrated genomics approach for novel biomarker discovery in squamous cell cervical carcinoma
Detection of copy number dependent gene expression profiles in epithelial tumours has lead to the discovery of genes significant in diagnosis, prognosis and of therapeutic value. We sought to apply the technologies of gene expression profiling and copy number aberration detection by high density oli...
ORGANISM(S): Homo sapiens 
2011-03-05 | E-GEOD-27673 | biostudies-arrayexpress
TranscriptomicsGene expression analysis in a variety of normal, premalignant and squamous cell carcinomas of the cervix
We sought to apply the technologies of gene expression profiling to detect genes significant in the aetiology of cervical carcinoma . We investigated 14 normal (NAD), 11 low grade squamous intrapepithelial lesions (LSIL), 21 high grade squamous intraepithelial lesions (HSIL) and 28 squamous cell ca...
ORGANISM(S): Homo sapiens 
2013-09-17 | E-GEOD-27678 | biostudies-arrayexpress
TranscriptomicsFine-scale mapping of copy-number alterations with massively parallel sequencing
In order to benchmark the reproducibility of Affymetrix 238K Sty arrays for detecting copy-number alterations. We performed replicate hybridizations of 3 tumor cell lines and 2 paired normal cell lines obtained from the American Type Culture Collection (ATCC). We calculated copy numbers at each SNP...
ORGANISM(S): Homo sapiens 
2008-11-13 | E-GEOD-12019 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human actute monocytic leukemia cell line THP-1 cells incubated at 37 or 32 degrees C for 24h reveals moderate hypothermia produces substantial changes in cellular gene expression, in categories potentially of importance to systemic function.
Background: Moderate hypothermia (32oC for 12 – 72 hours) has therapeutic applications, but the mechanisms by which it affects cellular function are unclear. We tested the hypothesis that moderate hypothermia produces broad changes in gene expression by human cells at the level of mRNA. Methods:...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4425 | biostudies-arrayexpress
TranscriptomicsHigh-resolution mapping of copy-number alterations with massively parallel sequencing
In order to benchmark the reproducibility of Affymetrix Genome-Wide Human SNP Array 6.0 for detecting copy-number alterations, we performed replicate hybridizations of 3 tumor cell lines and 2 paired normal cell lines obtained from the American Type Culture Collection (ATCC). We calculated copy numb...
ORGANISM(S): Homo sapiens 
2008-11-13 | E-GEOD-13372 | biostudies-arrayexpress
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