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ProteomicsSepioloidea lineolata MSMS
Sepioloidea lineolata, the striped pyjama squid (family Sepiadariidae), is a small species of benthic squid distributed along the Southern Indo-Pacific coast of Australia. All sepiadariid squids are known to secrete large volumes of viscous slime when stressed. The proteome of S. lineolata slime wa...
ORGANISM(S): Sepioloidea lineolata 
2022-02-28 | PXD010283 | Pride
Glycosylation Squid Comparison Slime Cephalopod 
ProteomicsLabel-Free Quantiative Analysis of Sepioloidea lineolata
Sepioloidea lineolata, the striped pyjama squid (family Sepidariidae), is a small species of benthic squid distributed along the Southern Indo-Pacfic coast of Australia. All Sepiadariid squids are known to secrete large volumes of viscous slime when stressed. The proteome of the slime, dorsal and ve...
ORGANISM(S): Sepioloidea lineolata 
2020-02-25 | PXD013436 | Pride
Secretion Squid : slime Differential expression Gland Label-free quantitation Cephalopod 
ProteomicsSepiadarium austrinum Slime MSMS
Sepiadarium austrinum, the southern bottletail squid, is a small squid that inhabits soft sediments along Australia’s south-east coast. When provoked this squid rapidly secretes large volumes of slime as a defense mechanism. Behavioral observations suggest that this slime may be toxic to crabs but i...
ORGANISM(S): Sepiadarium austrinum 
2016-08-08 | PXD003207 | Pride
Squid Slime Orbitrap Cephalopod 
UnknownGlymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study.
Not available
S-EPMC11786353 | biostudies-literature
UnknownSprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men.
Not available
S-EPMC12769668 | biostudies-literature
UnknownImpairments in sleep and brain molecular clearance in people with cognitive deterioration and biological evidence of AD: a report of four cases.
Not available
S-EPMC10664290 | biostudies-literature
ProteomicsMitochondrial stress drives skeletal muscle remodelling following sprint-interval exercise.
Mitochondria play a central role in cellular metabolism and are crucial for maintaining cellular health. Exercise is a proven intervention to enhance mitochondrial function and prevent non-communicable diseases, yet the molecular mechanisms driving exercise-induced mitochondrial remodelling remain u...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD059070 | Pride
Exercise Mitochondria Muscle Dia Human 
ProteomicsUntargeted proteomics enables ultra-rapid variant prioritization in mitochondrial and other rare diseases
Only half of individuals with suspected rare diseases receive a definitive genetic diagnosis following genomic testing. A genetic diagnosis allows access to appropriate patient care and reduces the number of potentially unnecessary interventions and related healthcare costs. Here, we demonstrate tha...
ORGANISM(S): Homo sapiens (Human) 
2024-09-03 | PXD055473 | Pride
Human Fibroblasts Pbmcs Hek293t Orbitrap 
ProteomicsTraining-induced bioenergetic improvement in human skeletal muscle is associated with non-stoichiometric changes in the mitochondrial proteome without reorganisation of respiratory chain content
Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an accessible and inexpensive therapeutic intervention that can improve mitochondrial bioenergetics and quality of life. By combining a multi-omics approach with biochemical and in silico normalisation, we remo...
ORGANISM(S): Homo sapiens (Human) 
2021-09-30 | PXD026219 | Pride
Proteomics Lipidomics Exercise Oxphos Mitochondria Fat metabolism Energy metabolism Transcriptomics Human 
ProteomicsTEFM variants impair mitochondrial transcription elongation causing childhood-onset neurological disease
Mutations in either the mitochondrial or nuclear genomes are associated with a diverse group of human disorders characterized by impaired mitochondrial respiration. Within this group, an increasing number of mutations have been identified in nuclear genes involved in mitochondrial RNA biology. The T...
ORGANISM(S): Homo sapiens (Human) 
2022-11-07 | PXD030427 | Pride
Mitochondria Transcription Mitochondrial disease Rna 
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