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Seminal plasma proteins play critical roles in sperm function, motility, viability and oxidative stress regulation in stallions. In this study, label-free quantitative (LFQ) proteomics was applied to characterize seminal plasma protein signatures associated with sperm quality in Arabian stallions. S...
ORGANISM(S): Equus caballus (Horse) 
2026-05-25 | PXD078825 | Pride
The association between reduced myofilament force-generating capacity (Fmax) and heart failure (HF) is clear, however the underlying molecular mechanisms are poorly understood. Here, we show impaired Fmax arises from reduced BAG3-mediated sarcomere turnover. Myofilament BAG3 expression decreases in ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2020-11-06 | MSV000086422 | MassIVE
Genomics
Chemical Assessment of Surfaces and Air (CASA)
We generated a collection of 13 plasmids, with each plasmid containing a variant of a CRISPR protospacer targeted by spacer 8 of the E. coli CRISPR-I array. We transformed the plasmids as a pool into delta cas3 E. coli cells expressing all other cas genes constitutively, with FLAG-tagged casA. We th...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
Concatemer-assisted stoichiometry analysis (CASA) addresses a common challenge in cell biology: absolute quantification of protein subunits in native protein complexes.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-12-17 | PXD058295 | Pride
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