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TranscriptomicsSuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset
Monocytes are a heterogeneous cell population with subset-specific functions and phenotypes. The differential expression of CD14 and CD16 distinguishes classical CD14++CD16-, intermediate CD14++CD16+ and non-classical CD14+CD16++ monocytes. However, CD14++CD16+ monocytes remain the most poorly chara...
ORGANISM(S): Homo sapiens 
2011-07-24 | E-GEOD-30811 | biostudies-arrayexpress
TranscriptomicsGene expression of CD14+ cells from RA, PsA and PsO patients with Infliximab treatment
objection: The immune inflammatory disorders rheumatoid arthritis (RA), psoriatic arthritis (PsA) and psoriasis (Ps) share common pathologic features and show responsiveness to anti-tumor necrosis factor (TNF) agents yet they are phenotypically distinct. The aim of this study was to examine if anti-...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-GEOD-57383 | biostudies-arrayexpress
Proteomicstherapeutic CD14 heart proteome
Therapeutic remodelling and repair of murine heart induced by CD14 antibody treatment. Global (apex) heart and macrophage-derived (FACS) proteome remodelling of CD14 antibody-based therapeutic.
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD041192 | Pride
Mouse Macrophage Cd14 Therapeutic Proteome Repair 
TranscriptomicsA novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients
Tumor progression is associated with an immunosuppressive microenvironment that consists of several elements, such as regulatory T cells, type 2 macrophages and myeloid-derived suppressor cells. Here, we identify for the first time a BDCA1+CD14+ population of immunosuppressive cells that resides bot...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-75042 | biostudies-arrayexpress
TranscriptomicsGene expression of CD14- cells from RA, PsA and PsO patients with Infliximab treatment
objection: The immune inflammatory disorders rheumatoid arthritis (RA), psoriatic arthritis (PsA) and psoriasis (Ps) share common pathologic features and show responsiveness to anti-tumor necrosis factor (TNF) agents yet they are phenotypically distinct. The aim of this study was to examine if anti-...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-GEOD-57405 | biostudies-arrayexpress
TranscriptomicsRegulatory role of multinucleated giant cells derived from placental CD14+ macrophages: Pathophysiological implications
The role of placental macrophages is largely ignored in the success of pregnancy. We found that CD14+ macrophages purified from at-term placentas spontaneously matured into multinucleated giant cells (MGCs). MGCs lost the expression of CD14 and co-inhibitory molecules, such as Programmed cell Death-...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-38747 | biostudies-arrayexpress
ProteomicsDifferential proteomics of peripheral blood CD14+ monocytes in the luminal breast carcinoma subtypes: A primary study
We performed differential proteomic analysis of CD14+ monocytes from peripheral blood of BC-confirmed patients, benign individuals vs. HCs. Results revealed DEPs found across all studied cohorts such as SRSF1, CSTB, KRT2, KRT5, HEL-S-11, APOB, APOE, and ITGA2B. Herein, APOB, HEL-S-11, KRT5, and SRS1...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD068744 | Pride
Breast cancer Lc-msms B-cell lymphocytes Blood Human 
TranscriptomicsGene expression profiling of the classical (CD14++CD16-), intermediate (CD14++CD16+) and nonclassical (CD14+CD16+) human monocyte subsets
The new official nomenclature subdivides human monocytes into three subsets, classical (CD14++CD16-), intermediate (CD14++CD16+) and nonclassical (CD14+CD16+). Here, we comprehensively define relationships and unique characteristics of the three human monocyte subsets using microarray and flow cytom...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-25913 | biostudies-arrayexpress
TranscriptomicsCirculating Mononuclear Cell Transcriptomes in Patients with Atherosclerotic Coronary Artery Disease
Monocytes and T-cells play an important role in the development of atherosclerotic coronary artery disease (CAD). Differences in transcriptional activity of these cells might reflect the individual's atherosclerotic burden. Transcriptome analysis of circulating mononuclear cells from carefully match...
ORGANISM(S): Homo sapiens 
2008-12-01 | E-GEOD-9820 | biostudies-arrayexpress
TranscriptomicsCD14+ cell analysis
Comparison of gene expression in CD14 cells from peripheral blood and G-CSF-mobilized peripheral blood to investigate why the latter may be beneficial for allogeneic transplant recipients. Samples from 2-3 donors were pooled for each sample. All cells were freshly isolated after ficoll separation of...
ORGANISM(S): Homo sapiens 
2007-08-21 | E-GEOD-1746 | biostudies-arrayexpress
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