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TranscriptomicsOntogeny of CD24 expression in the human fetal kidney
CD24, or heat stable antigen, is a cell surface sialoglycoprotein expressed on immature cells that disappears after the cells have reached their final differentiation stage. CD24 may be important in human embryonic kidney epithelial cell differentiation. In mice, CD24 expression is up-regulated in t...
ORGANISM(S): Homo sapiens 
2009-11-11 | E-GEOD-18969 | biostudies-arrayexpress
TranscriptomicsCD24 targets
Gene expression were identified with or without CD24 gene silencing in Du145 cells. RNA isolated from 5 independent cultures of Scramble control, 3 cultures of CD24-ShRNA1 and 2 cultures of CD24-ShRNA2 were tested using Affimatrx Human U133 Plus 2.0 microarrays.
ORGANISM(S): Homo sapiens 
2014-05-05 | E-GEOD-46708 | biostudies-arrayexpress
TranscriptomicsTargetting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or siRNA
CD24 is a potential oncogene reported to be overexpressed in a large variety of human malignancies. We have shown that CD24 is overexpressed in 90% of colorectal tumors at a fairly early stage in the multistep process of carcinogenesis. Anti-CD24 monoclonal antibodies (mAb) induce a significant grow...
ORGANISM(S): Homo sapiens 
2009-03-07 | E-GEOD-15102 | biostudies-arrayexpress
ProteomicsMolecular and epigenetic characterization of the signal transducer CD24 in germ cell tumors
Type II germ cell tumors (GCTs) are with more than 90% the most common neoplasia in young men of age 14 - 45 years. It is generally accepted that GCTs arise from a common precursor lesion, called germ cell neoplasia in situ (GCNIS), eventually developing into seminomas or non-seminomas. The non-sem...
ORGANISM(S): Homo sapiens (Human) 
2022-01-19 | PXD025110 | Pride
Epigenetics Pluripotency Embryonal carcinoma Differentiation Cd24 Germ cell tumors 
ProteomicsIdentification of CD24 interaction partners in urologic tumor cell lines
Being involved in adhesion, migration, and invasion, the highly glycosylated signal transducer CD24 (cluster of differentiation 24) has been implicated to play an essential role during carcinogenesis. Previously, the molecular and (epi)genetic regulation of CD24 has been characterized in testicular ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD039063 | Pride
Germ cell tumor Cd24 Urothelial carcinoma Renal cell carcinoma Co-immunoprecipitation Prostate cancer 
TranscriptomicsTranscription profiling of human normal, non-tumorigenic breast cancer cells and CD44+CD24-/low tumorigenic breast cancer cells to generate a invasiveness gene signature
Breast cancers contain a minority population of cancer cells characterized by CD44 expression but low or undetectable levels of CD24 (CD44+CD24-/low) that have higher tumorigenic capacity than other subtypes of cancer cells. METHODS: We compared the gene-expression profile of CD44+CD24-/low tumorige...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-6883 | biostudies-arrayexpress
TranscriptomicsDifferences between CD44+/CD24- and CD44-/CD24+ subpopulation of immortalized human mammary epithelial cells
CD44+/CD24- subpopulation of normal and cancerous breast epithelial cells are suggested to have stem cell properties. The goal of this study was to identify gene expression differences between CD44+/CD24- and CD44-/CD24+ subpopulation of cells from a same cell lines. We selected MCF-10A cells, which...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-GEOD-15192 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in human mammary epithelial cell (HMEC) CD24-CD44+ and non-CD24-CD44+ cell populations
To understand the role of p53 in regulating stem cell population (CD24-CD44+) and stemness-associated miRNAs, we first compared miRNA expression profiles between human mammary epithelical cells knocked-down p53 and control cells. We then cross-referenced p53-regulated miRNAs with stemness-associated...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-25036 | biostudies-arrayexpress
TranscriptomicsExpression data comparing Huh7 cells transduced with shRNA CD24 (knockdown) or non-target control
To identify CD24 signaling pathway Affymetrix Human Genome U133 Plus GeneChip 2.0 shRNA CD24 (knockdown) or non-target control (NTC) was stably transduced into Huh7 HCC cells by lentiviral approach
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-28057 | biostudies-arrayexpress
GenomicsCD24+ and CD24- myeloma-derived cancer stem cell lines
CD24+ and CD24- myeloma-derived cancer stem cell lines
PRJNA431593 | ENA
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