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ProteomicsA conserved AAA+ ATPase network regulates endoplasmic reticulum stress-induced transcription
In C. elegans cdc-48.2(-/-) mutant animals, ER stress-mediated expression of the UPR ckb-2::GFP reporter transgene is abolished. Here, we have used this phenotype in a genome-wide RNAi screen to identify genes involved in the CDC-48.2 mediated ER stress transcription. Combined with a comparative pro...
ORGANISM(S): Caenorhabditis elegans 
2015-09-30 | PXD000636 | Pride
Proteomic screen C. elegans Reptin Cdc-48 Rnai screen Vcp Endoplasmic reticulum stress P97 Ruvb-2 
ProteomicsProteomic analysis of leucine effect on OMM protein turnover in C. elegans overexpressing cdc-48
This project is to investigate whether and how leucine affects endogenous OMM protein stability in C. elegans overexpressing cdc-48. Whole worm and enriched mitochondria samples (with/without leucine and/or CHX treatment) were measured.
ORGANISM(S): Caenorhabditis elegans 
2025-11-05 | PXD062736 | Pride
Leucine Mitochondria Protein turnover Outer mitochondrial membrane 
UnknownCDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication.
Not available
S-EPMC3428722 | biostudies-literature
ProteomicsER-stress-induced_transcription
A conserved AAA+ ATPase network regulates ER-stress-induced transcription
ORGANISM(S): Caenorhabditis Elegans (c. Elegans) 
2015-12-31 | PAe005594 | PeptideAtlas
UnknownGenome-wide screen identifies a novel p97/CDC-48-dependent pathway regulating ER-stress-induced gene transcription.
Not available
S-EPMC4364872 | biostudies-literature
UnknownSKN-1 activation during infection of Caenorhabditis elegans requires CDC-48 and endoplasmic reticulum proteostasis.
Not available
S-EPMC11538416 | biostudies-literature
UnknownGTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48.
Not available
S-EPMC2447140 | biostudies-literature
TranscriptomicsMicroarray analysis of WT bone marrow myeloid progenitors, BM cultured with GM-CSF and M-CSF, and monocytes treated with GM-CSF
Analysis of genes induced in DC precursors and in BM cells and monocytes treated with GM-CSF For progenitor arrays, bone marrow progenitors (CMP, GMP, CDP, and pre-cDC) were harvested from WT C57Bl/6 mice. For culture arrays, BM was cultured in the presence of GM-CSF or M-CSF and adherent and non-a...
ORGANISM(S): Mus musculus 
2012-05-20 | E-GEOD-37029 | biostudies-arrayexpress
UnknownCell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication.
Not available
S-EPMC2529102 | biostudies-literature
UnknownDual Surveillance of Surgical Site Infections Using CDC and ASEPSIS Criteria: Clinical and Economic Outcomes in Colorectal and Small Bowel Surgery.
Not available
S-EPMC12582140 | biostudies-literature
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