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Characterization of proteins in extracellular vesicles (EV) from cardiosphere-derived cells (CDCs) of a clinically relevant pig model. Additionally, considering that priming stem cells with inflammatory stimuli may increase the therapeutic potential of released vesicles, here we studied the dynamic ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-05-15 | PXD016434 | Pride
Some studies report better outcomes in cell therapy for myocardial infarction (MI) with repeated administrations. We aimed to elucidate the potential differences in terms protein expression after one or three doses of cardiosphere-derived cells (CDCs) in a porcine MI model. CDCs were isolated from s...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-12-22 | PXD070301 | Pride
comparison of primary epicardium explant derived CDCs and primary Epicardial cells
Here, we use a microfluidics-based approach to prepare single-cell RNA-Seq libraries from 164 primary human conventional dendritic cells (cDCs) as well as cord blood (452) and blood (341) pre-cDCs. We examined heterogeneity between individual cells to document potential subpopulations within human c...
ORGANISM(S): Homo sapiens 
2016-11-15 | GSE89232 | GEO
The analysis showed differences of transcriptomes between primary epicardium explant derived CDCs and primary Epicardial cells directly isolated from the heart epicardium.SB-431542 was an effective TGF-b pathway inhibitor that could obviously inhibit the epicardial cells Epithelial-mesenchymal trans...
ORGANISM(S): Mus musculus 
2022-02-18 | GSE189275 | GEO
Early transcriptional signature in murine cDCs post immunisation with VLPs containing TLR ligands
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