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TranscriptomicsNsaRS is a Cell-Envelope-Stress Sensing Two-Component System of Staphylococcus aureus
S. aureus possesses 16 two-component systems (TCS), two of which (GraRS & NsaRS) belong to the intramembrane-sensing histidine kinase (IM-HK) family, conserved within the firmicutes. NsaRS has recently been documented as being important for nisin-resistance in S. aureus. In this study we present a d...
ORGANISM(S): Staphylococcus aureus 
2011-05-16 | E-GEOD-27061 | biostudies-arrayexpress
ProteomicsUnravelling hidden components of the chloroplast envelope proteome
Chloroplast is a major plant cell organelle that fulfills essential metabolic and biosynthetic functions. Located at the interface between the chloroplast and other cell compartments, the chloroplast envelope system is a strategic barrier controlling exchanges of ions, metabolites and proteins, thus...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-15 | PXD010545 | Pride
Lc-msms Chloroplast Arabidopsis Envelope 
ProteomicsLEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
Quantitative crosslinking analysis to probe in vitro conformational dynamics governing ESCRT-mediated nuclear envelope formation. CHMP7 was crosslinked with D12-BS3 while CHMP7 in the presence of LEM2 winged helix domain was crosslinked with H12-BS3. Samples were mixed after crosslinking and analy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-24 | MSV000084837 | MassIVE
ProteomicsComparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
The nuclear envelope (NE) is a subdomain of the ER with a distinctive protein composition that underpins its role in nuclear compartmentalization. To expand an understanding of NE functions, we refined methods to reveal low abundance transmembrane (TM) proteins concentrated at the NE. De facto, th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-01-25 | MSV000091154 | MassIVE
MetabolomicsExploring the effect of estrogen on Candida albicans hyphal cell wall glycans and ergosterol synthesis
Increased levels of 17-β estradiol (E2) due to pregnancy in young women or to hormonal replacement therapy in postmenopausal women have long been associated with an increased risk of yeast infections. Nevertheless, the effect underlying the role of E2 in Candida albicans infections is not wel...
2025-09-11 | MTBLS5821 | MetaboLights
TranscriptomicsThe cell envelope stress response mediated by the LiaFSRLm three-component system of Listeria monocytogenes is controlled via the phosphatase activity of the bifunctional histidine kinase LiaSLm
Most members of the phylum Firmicutes harbor a two-component system, LiaSR, which is involved in the response to cell envelope stress elicited most notably by inhibitors of the lipid II cycle. In all LiaSR systems studied in detail LiaSR-mediated signal transduction was shown to be negatively contro...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-11-16 | E-GEOD-24107 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C2C12 cells cultured either in 20% serum (undifferentiated) or in 2% horse serum (differentiated) to detail the global changes of gene expression in lamins and nuclear envelope assoicated proteins during myogenesis
During muscle differentiation, myogenesis sepcific genes are differentially regulated, including Lamins that function at least in maintenance of nuclear architecture and regulation of gene expression. We used microarrays to detail the global changes of gene expression in lamins and nuclear envelope ...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-4694 | biostudies-arrayexpress
ProteomicsIdentification of chloroplast envelope proteins with critical importance for cold acclimation
Differential proteome analysis allowed to identify envelope proteins critical for cold acclimation and frost tolerance in Arabidopsis thaliana.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-12-08 | PXD015794 | Pride
Ntt Shotgun proteomics Envelope Mex1 Chloroplast Proteomics 
ProteomicsDisulfide bonds are critical for stabilizing cell division, cell envelope biogenesis, and antibiotic resistance proteins in mycobacteria
Mycobacterium, including Mycobacterium tuberculosis, the etiological agent of tuberculosis, have a unique cell envelope critical for their survival and antibacterial resistance. The cell envelope's assembly and maintenance influence permeability, making it a key target against multidrug resistant st...
ORGANISM(S): Mycobacterium Smegmatis Str. Mc2 155 (ncbitaxon:246196) 
2025-01-16 | MSV000096877 | MassIVE
MetabolomicsNitrate Reductase NarGHJI Modulates Vancomycin Susceptibility by Coordinating Cell Wall Remodeling and Agmatine Metabolism in Staphylococcus aureus
Staphylococcus aureus is a ubiquitous pathogen responsible for a wide range of severe infections. Our previous work established that the nitrate reductase NarGHJI modulates bacterial pathogenicity through regulation of the agr system, yet its role in antibiotic resistance remains poorly understood. ...
2026-07-07 | MTBLS14968 | MetaboLights
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