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ProteomicsPI3K-AKT pathway and cell-cell contact regulates maspin nuclear localization
Background: Maspin (SERPINB5) is a potential tumor suppressor gene with pleiotropic biological activities, including regulation of cell proliferation, death, adhesion, migration and gene expression. Several studies indicate that nuclear localization is essential for maspin tumor suppression activity...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023224 | Pride
Cell-to-cell contact Jak-stat Maspin Egfr Pi3k-akt 
ProteomicsPulldown of Maspin-GST in Human Cells Treated or Untreated with Nocodazole
Human cells, either asynchronous or synchronized with nocodazole, were subjected to a pulldown assay using GST-maspin. Interacting proteins were eluted using 10 mM reduced glutathione, 150 mM NaCl, 1 mM DTT, and 50 mM Tris-HCl (pH 8.5).
ORGANISM(S): Homo sapiens (Human) 
2025-09-01 | PXD057847 | Pride
Pulldown Human cells Nocodazole Maspin 
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