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Proteomicsimmunoprecipitation coupled with a mass spectrometry (MS) approach to identify cellular proteins associated with MOV10
To understand the detailed mechanism underlying MOV10-mediated restriction of LINE-1 retrotransposition, we first performed immunoprecipitation coupled with a mass spectrometry (MS) approach to identify cellular proteins associated with MOV10.
ORGANISM(S): Homo sapiens (Human) 
2023-08-30 | PXD041814 | Pride
Mass，mov10 Ip 
ProteomicsAn anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA
The emergence of new highly pathogenic and drug-resistant influenza strains urges the development of novel therapeutics for influenza A virus (IAV). Here, we report the discovery of an anti-IAV microbial metabolite called APL-16-5 that was originally isolated from the plant endophytic fungus Aspergi...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD031993 | Pride
Influenza a virus  proteolysis-targeting chimeras  trim25  phenalenone derivatives  microbial metabolites  antiviral drug 
ProteomicsSARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis
The coronavirus disease 2019 (COVID-19) pandemic has devastated global health. Identifying key host factors essential for SARS-CoV-2 RNA replication is expected to unravel cellular targets for the development of broad-spectrum antiviral drugs which have been quested for the preparedness of future vi...
ORGANISM(S): Homo Sapiens 
2022-09-28 | PXD037068 |
UnknownTeicoplanin derivatives block spike protein mediated viral entry as pan-SARS-CoV-2 inhibitors.
Not available
S-EPMC9808420 | biostudies-literature
UnknownSpecific Spoilage Bacterium of Chilled Sturgeon Fillets and the Bacterial Reduction Effect of ClO<sub>2</sub>.
Not available
S-EPMC12554782 | biostudies-literature
ProteomicsProteome Changes of Sheep Rumen Epithelium during Post-natal Development
a shotgun approach and bioinformatics analyses to investigate and compare proteomic profile of sheep rumen epithelium tissue on day 0, 15, 30, 45 and 60 of age.
ORGANISM(S): Ovis aries 
2023-03-11 | PXD034787 | Pride
Sheep  rumen epithelium  lc-ms  postnatal development 
UnknownBRAF Mutation as a Potential Therapeutic Target for Checkpoint Inhibitors: A Comprehensive Analysis of Immune Microenvironment in BRAF Mutated Colon Cancer.
Not available
S-EPMC8350390 | biostudies-literature
UnknownMicroRNA hsa-miR-623 directly suppresses MMP1 and attenuates IL-8-induced metastasis in pancreatic cancer.
Not available
S-EPMC6561617 | biostudies-literature
UnknownA small molecule compound IMB-LA inhibits HIV-1 infection by preventing viral Vpu from antagonizing the host restriction factor BST-2.
Not available
S-EPMC4680884 | biostudies-literature
ProteomicsThe essential role of stress granules in cGAS sensing of DNA
cGAS-associated cellular proteins through performing co-immunoprecipitation (co-IP) followed by mass spectrometry and proteomic analysis
ORGANISM(S): Homo Sapiens 
2019-02-24 | PXD012847 |
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