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TranscriptomicsA Human Model of Cerebral Amyloid Angiopathy Using Neural Crest-Derived Vascular Smooth Muscle Cells
There is a growing recognition of cerebrovascular contribution to neurodegenerative diseases. Cerebral amyloid angiopathy (CAA), characterised by amyloid-beta (AM-NM-2) deposits in the walls of intracerebral and leptomeningeal arteries, is evident in a majority of AlzheimerM-bM-^@M-^Ys disease patie...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-55173 | biostudies-arrayexpress
ProteomicsParenchymal and Dyshorric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2
Whole brain tissue proteomics from rat models of cerebral small vessel disease and Alzheimer's disease, including the rTg-DI model of Cerebral Amyloid Angiopathy (CAA) Type-1, the rTg-D model of CAA Type-2 with both hemizygous and homozygous animals, and the TgSD-AD model of Alzheimer's Disease.
ORGANISM(S): Rattus norvegicus (Rat) 
2025-11-17 | PXD061304 | Pride
Cerebral amyloid angiopathy Preclinical model Alzheimer's disease Cerebral small vessel disease 
ProteomicsDifferences in the Cerebral Amyloid Angiopathy Proteome in Alzheimers Disease and Mild Cognitive Impairment
Quantitative label-free proteomics study comparing brain samples from subjects with Cerebral amyloid angiopathy, Alzheimer desease and healthy Control groups.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-03-25 | MSV000094400 | MassIVE
UnknownAnti-Aβ Autoantibodies in Amyloid Related Imaging Abnormalities (ARIA): Candidate Biomarker for Immunotherapy in Alzheimer's Disease and Cerebral Amyloid Angiopathy.
Not available
S-EPMC4585101 | biostudies-literature
ProteomicsMulti-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of specific proteins and heparan sulfate disaccharides
Cerebral amyloid angiopathy (CAA) is a common feature of Alzheimer’s disease in which amyloid-β (Aβ) deposits in cerebral and leptomeningeal vessel walls, predisposing to micro- and macro-hemorrhage. The vessel wall has distinct proteins and heparan sulfate (HS), linear polysaccharides that bind Aβ ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056864 | Pride
Human amyloid meningeal proteomics 
ProteomicsProteome analysis of microvessels from CAA and AD patients
Cerebral amyloid angiopathy (CAA) is an age-related condition and a major cause of intracerebral hemorrhage and cognitive decline that shows close links with Alzheimer's disease (AD). CAA is characterized by the aggregation of amyloid-β (Aβ) peptides and formation of Aβ deposits in the brain vascula...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD029380 | Pride
Proteomics Cerebral amyloid angiopathy Cadasil Cerebral small vessel disease Proteostasis Htra1 
GenomicsChronic Stress Exacerbates Cerebral Amyloid Angiopathy through Promoting NET formation [I]
Chronic Stress Exacerbates Cerebral Amyloid Angiopathy through Promoting NET formation [I]
PRJNA1051140 | ENA
GenomicsChronic Stress Exacerbates Cerebral Amyloid Angiopathy through Promoting NET formation [II]
Chronic Stress Exacerbates Cerebral Amyloid Angiopathy through Promoting NET formation [II]
PRJNA1051139 | ENA
GenomicsBrain transcriptome of hereditary cerebral haemorrhage with amyloidosis–Dutch type (HCHWA-D)
HCHWA-D is an early onset hereditary form of Cerebral Amyloid Angiopathy (CAA) caused by a point mutation resulting in an amino acid change (NP_000475.1:p.Glu693Gln) in the Amyloid Precursor Protein (APP). Post-mortem brain tissue (9 patients and 9 age-related controls; frontal and occipital cortex)...
EGAS00001002730 | EGA
TranscriptomicsExploration of common pathogenic genes between cerebral amyloid angiopathy and insomnia based on bioinformatics and experimental validation
RNA transcriptome analysis results were utilized to assess the shared gene expression between patients with cerebral amyloid angiopathy (CAA) and those with insomnia.
ORGANISM(S): Homo sapiens 
2025-07-30 | GSE289809 | GEO
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