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MetabolomicsMetabolome of 334 cerebral thrombi (in four batches) retrieved by mechanical thrombectomy after ischemic stroke due to large vessel occlusion (Retro-MATISSE study)

The Retro-MATISSE study (Molecular Analysis of Thrombus for Ischemic Stroke prognosiS and Etiology) aimed to characterize the metabolome of 334 thrombi <...

2026-04-25 | MTBLS14374 | MetaboLights
ProteomicsProteome analysis of brain vessels (the anterior cerebral artery and the middle cerebral artery) from 24-month-old Htra1 KO and wild type mice
CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary cerebral small-vessel disease caused by loss of function mutations of HTRA1, which is a serine protease with a variety of targets, including extracellular matrix proteins. We isolate...
ORGANISM(S): Mus Musculus (mouse) 
2021-11-02 | PXD022298 | JPOST Repository
ProteomicsProteome analysis of brain vessels (the anterior cerebral artery and the middle cerebral artery) from 24-month-old candesartan-treated and nontreated Htra1 KO mice
CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary cerebral small-vessel disease caused by loss of function mutations of HTRA1, which is a serine protease with a variety of targets, including extracellular matrix proteins. Htra1-KO m...
ORGANISM(S): Mus Musculus (mouse) 
2021-11-16 | PXD023477 | JPOST Repository
ProteomicsAttenuated inflammatory profile following single and repeated handgrip exercise and remote ischemic preconditioning in patients with cerebral small vessel disease
Similar to remote ischemic preconditioning bouts of exercise may possess immediate protective effects against ischemia-reperfusion injury. However, underlying mechanisms are largely unknown. This study compared the impact of single and repeated handgrip exercise versus remote ischemic preconditionin...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037267 | Pride
Exercise Inflammation Remote ischemic preconditioning Cerebral small vessel disease Proteomics. 
ProteomicsEffect of age on the vascular proteome in middle cerebral arteries and small mesenteric arteries in mice
Effect of age on the vascular proteome in middle cerebral arteries and small mesenteric arteries in mice
ORGANISM(S): Mus Musculus (mouse) 
2022-02-09 | PXD024070 | JPOST Repository
GenomicsCerebrovascular p16INK4A expression induces cerebral small vessel disease-related phenotypes
Cerebrovascular p16INK4A expression induces cerebral small vessel disease-related phenotypes
PRJNA1302351 | ENA
GenomicsHTRA1 Mutation and Expression Regulation in Cerebral Small Vessel Disease
HTRA1 Mutation and Expression Regulation in Cerebral Small Vessel Disease
PRJNA1433271 | ENA
TranscriptomicsTranscription profiling of rat arteries from animals with salt induced hypertensive disease results in over expression of matricellular genes in cerebral arteries
The Dahl salt-sensitive (S) rat model develops chronic hypertensive disease when fed a high salt diet that ultimately results in renal and heart failure, as well as prevalent cerebrovascular pathologies. Phenotypic changes in the cerebral vasculature are preceded by changes in gene expression, and ...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5488 | biostudies-arrayexpress
GenomicsPro-inflammatory monocyte phenotype during acute progression of cerebral small vessel disease
Pro-inflammatory monocyte phenotype during acute progression of cerebral small vessel disease
PRJNA683025 | ENA
ProteomicsParenchymal and Dyshorric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2
Whole brain tissue proteomics from rat models of cerebral small vessel disease and Alzheimer's disease, including the rTg-DI model of Cerebral Amyloid Angiopathy (CAA) Type-1, the rTg-D model of CAA Type-2 with both hemizygous and homozygous animals, and the TgSD-AD model of Alzheimer's Disease.
ORGANISM(S): Rattus norvegicus (Rat) 
2025-11-17 | PXD061304 | Pride
Cerebral amyloid angiopathy Preclinical model Alzheimer's disease Cerebral small vessel disease 
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