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ProteomicsExtracellular vesicle membrane protein profiling and targeted mass spectrometry unveil novel plasma biomarkers for detection of colorectal cancer
Extracellular vesicles (EVs) are valuable sources for the discovery of useful cancer biomarkers. This study explores the potential usefulness of tumor cell-derived EV membrane proteins as plasma biomarkers for early detection of colorectal cancer (CRC). EVs were isolated from the culture supernatant...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD038871 | Pride
Extracellular vesicles Colorectal cancer Targeted mass spectrometry Membrane protein Itraq Aims 
UnknownRobot-assisted vs. laparoscopic right hemicolectomy in octogenarians and nonagenarians: an analysis of the US nationwide inpatient sample 2005-2018.
Not available
S-EPMC11420325 | biostudies-literature
ProteomicsCholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium
Cellular locations of (Cholesteryl α-D-glucoside 6-acyltransferase) CGAT To study the cellular location of CGAT, based on our pervious experiments, the CGAT activity was observed in the outer membrane vesicles (OMVs), rather than in the culture medium, suggesting that CGAT resided in the outer mem...
ORGANISM(S): Helicobacter pylori 26695 
2020-03-19 | PXD017518 | Pride
Helicobacter pylori Cholesteryl glucoside Acyltransferase Lipid raft Outer membrane vesicle Integrin 
UnknownSkin Autofluorescence Is Associated with Endothelial Dysfunction in Uremic Subjects on Hemodialysis.
Not available
S-EPMC4726548 | biostudies-literature
ProteomicsLC-MS/MS analysis of pancreatic cancer plasma
Pancreatic cancer (PC) is an aggressive cancer with a high mortality rate, necessitating the de-velopment of effective diagnostic, prognostic and predictive biomarkers for disease manage-ment. Aberrantly fucosylated proteins in PC are considered a valuable resource of clinically useful biomarkers. T...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD025150 | Pride
Itraq-based quantitative proteome Pancreatic cancer Aal Fucosylated serpina1 Plasma Glycobiomarker Reverse lectin-based elisa 
UnknownAdjuvant heparanase inhibitor PI-88 therapy for hepatocellular carcinoma recurrence.
Not available
S-EPMC4145780 | biostudies-literature
ProteomicsLC-MS/MS analysis of human thyroid cystic fluid and thyroid cancer cell secreted proteins
Thyroid ultrasound and ultrasound-guided fine-needle aspiration (USG/FNA) biopsy are currently used for diagnosing papillary thyroid carcinoma (PTC), but their detection limit could be improved by combining other biomarkers. To discover novel PTC biomarkers, we herein applied a GeLC-MS/MS strategy t...
ORGANISM(S): Homo sapiens (Human) 
2018-03-21 | PXD007532 | Pride
Human Thyroid cystic fluid Thyroid cancer cell Lc-ms/ms 
ProteomicsIdentification of miR-16/29 targets in adipocytes by LC-MSMS
Cancer cachexia is a multifactorial metabolic syndrome defined by the rapid loss of skeletal muscle mass and the loss of fat mass. Up 80% of cancer patients at the late stage with cachexia suffer from progressive atrophy of adipose tissue. Unlike studies on skeletal muscle wasting, there is limited ...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-13 | PXD037998 | Pride
Lc-msms Mouse Adipocytes Mirnas 
ProteomicsIdentification of miR-16/29 targets in adipocytes by LC-MSMS
Cancer cachexia is a multifactorial metabolic syndrome defined by the rapid loss of skeletal muscle mass and the loss of fat mass. Up 80% of cancer patients at the late stage with cachexia suffer from progressive atrophy of adipose tissue. Unlike studies on skeletal muscle wasting, there is limited ...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-13 | PXD037862 | Pride
Lc-msms Mouse Adipocytes Mirnas 
TranscriptomicsMethylation profiling of oral squamous cell carcinoma (OSCC)
According to epidemiological studies, a vast majority, approximately 80%~90% of male OSCC patients in Taiwan habitually drink alcohol (A), and chew betel quid (B), and use cigarette (C). To assess the impact of these dietary factors on the epigenome, we conduct a high-throughput screen survey in an ...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-38532 | biostudies-arrayexpress
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