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TranscriptomicsmRNA Decay in E. Coli Degradosome Mutants and their Parental Strains
mRNA decay in E. Coli degradosome mutants and their parental strains following transcriptional arrest with rifampicin. Abstract: RNase E, an essential endoribonuclease of Escherichia coli, interacts through its C-terminal region with multiple other proteins to form a complex termed the RNA degradoso...
ORGANISM(S): Escherichia coli 
2006-01-05 | E-GEOD-3978 | biostudies-arrayexpress
ProteomicsProteotoxicity caused by perturbed protein complexes underlies hybrid incompatibility
Dobzhansky-Muller incompatibilities represent a major driver of reproductive isolation between species. They are caused when two or more interacting components encoded by alleles from different species cannot function properly when mixed. At incipient stages of speciation, complex incompatibilities ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-05 | PXD028358 | Pride
Epistasis Protein complex Proteotoxicity Proteostasis Speciation Genetic incompatibility 
UnknownRecurrent TTN metatranscript-only c.39974-11T>G splice variant associated with autosomal recessive arthrogryposis multiplex congenita and myopathy.
Not available
S-EPMC7306402 | biostudies-literature
ProteomicsComprehensive understanding the molecular components of LTBR signalling complex in cancers
Lymphotoxin beta receptor (LTBR), a member of TNFRSF, was identified as a key regulator in the development, organization, and homeostasis of lymphoid tissues (Wolf, Seleznik, Zeller, & Heikenwalder, 2010). Recently, LTBR has been shown to play a role in tumor biology, both in solid tumors and in hem...
ORGANISM(S): Homo sapiens (Human) 
2025-04-01 | PXD034142 | Pride
Human Ap-ms Lc-ms Lfq 
UnknownEngineering Protein Nanoparticles Functionalized with an Immunodominant Coxiella burnetii Antigen to Generate a Q Fever Vaccine.
Not available
S-EPMC10515490 | biostudies-literature
ModelsThiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0)
Thiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0) This model is described in the article: A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. Thiele I, Hyduke DR, Steeb B, Fankam ...
2015-07-30 | MODEL1507180017 | BioModels
TranscriptomicsHuman nasopharyngeal carcinoma
To uncover the oncogenic pathways of nasopharyngeal carcinoma, gene expression profiles of primary NPC cell strains and NPC-derived cell lines were conducted and analyzed in depth. Keywords: Oncogenesis Gene expression profiles of 9 primary NPC cell strains and 5 NPC-derived cell lines were analyz...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-14262 | biostudies-arrayexpress
UnknownThe utility of Aspirin in Dukes C and High Risk Dukes B Colorectal cancer--the ASCOLT study: study protocol for a randomized controlled trial.
Not available
S-EPMC3271983 | biostudies-literature
TranscriptomicsGene expression profiling of oral cancer cell lines with or without AzC treatment
To genome-wide screening for the genes whose expression are responsible for the promoter DNA methylation, we performed the cDNA microarray with oral cancer cells before and after a DNA methyltransferase inhibitor, 5-aza-2’-deoxycytidine (AzC), treatment. Total RNA was collected from four oral cancer...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-38823 | biostudies-arrayexpress
UnknownComparing Low- or Standard-Dose Alteplase in Endovascular Thrombectomy: Insights From a Nationwide Registry.
Not available
S-EPMC10896194 | biostudies-literature
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