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MetabolomicsThe timing of bacterial mesophyll infection shapes the leaf chemical landscape during the interaction

Chemistry in eukaryotic intercellular spaces is shaped by both hosts and symbiotic microorganisms such as bacteria. Pathogenic microorganisms like barley associated Xanthomonas translucens (Xt) swiftly overtake the inner leaf tissue becoming the dominant microbial community member during disease ...

2024-02-01 | MTBLS7676 | MetaboLights
MetabolomicsAdvancing Reef Monitoring Techniques through Exometabolomics: Quantification of Labile Dissolved Organic Metabolites on Coral Reefs

Extracellular chemical cues constitute much of the language of life among marine organisms from microbes to mammals. These chemical cues shape foraging and feeding strategies, symbiotic interactions, selection of mates and habitats, and the transfer of energy and nutrient...

2025-07-16 | MTBLS9008 | MetaboLights
MetabolomicsUntargeted metabolomic profiling reveals lineage-associated chemical divergence in Ophiorrhiza sensu lato
This study performed untargeted LC–MS metabolomic profiling of fresh leaf tissues from seven representative Ophiorrhiza sensu lato taxa: O. subpunicea, O. cantonensis, O. pumila, O. shiqianensis, O. humilis, O. huanjiangensis, and O. hispidula. Metabolites were extracted using a methanol–acetonitril...
2026-07-21 | MTBLS15110 | MetaboLights
ProteomicsLysargiNase and Chemical Derivatization Based Strategy for 2 Facilitating In-Depth Profiling of C‑Terminome
we developed a new method for C-terminomics, in which LysargiNase and chemical derivatization were integrated to increase the identification confidence.
ORGANISM(S): Homo Sapiens 
2019-12-16 | PXD016756 |
ProteomicsArg-C Ultra simplifies histone preparation for LC-MS/MS
Using mammalian histone extract, we demonstrate that Arg-C Ultra facilitates histone preparation for LC-MS/MS. We show the performance of Arg-C Ultra in terms of digestion specificity, number of modified forms identified, and yield of quantitative information compared with standard Arg-C and trypsin...
ORGANISM(S): Homo sapiens (Human) 
2025-06-30 | PXD059514 | Pride
Histone Arg-c ultra Trimethylacetic anhydride Lc-ms/ms Chemical derivatization 
UnknownChemical derivatization strategies for enhancing the HPLC analytical performance of natural active triterpenoids.
Not available
S-EPMC11010456 | biostudies-literature
ProteomicsReversible Lysine Derivatization Enables High Specificity of Arg-C Digestion Using Trypsin
Bottom-up proteomics approach has become an important strategy in diverse areas of biological research, and the enzymatic digestion is essential for this technology. Endopeptidase Arg-C catalyzing the hydrolytic cleavage of peptide bonds C-terminal to arginine could be an important protease in botto...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2018-01-04 | PXD007994 | Pride
Proteomics Arg-c Trypsin Lys-c Citraconylation Lc-ms/ms 
UnknownDetecting the Major Degradation Products of Phosphorothioate Oligonucleotides by Chemical Derivatization and Weak Anion Exchange Chromatography.
Not available
S-EPMC11618427 | biostudies-literature
UnknownChemical Derivatization of Affinity Matrices Provides Protection from Tryptic Proteolysis.
Not available
S-EPMC6872193 | biostudies-literature
ProteomicsCleavable Hydrophobic Derivatization Strategy for Enrichment and Identification of Phosphorylated Lysine Peptides
Herein, a cleavable hydrophobic derivatization (CHD) strategy was established for the enrichment and identification of pLys peptides. By CHD, 2,5-dioxopyrrolidin-1-yl-3-(decyldisulfanyl)propanoate (Dec-disulf-NHS) was synthesized to react with lysine dephosphorylated peptides, and then the derived p...
ORGANISM(S): Escherichia Coli 
2019-02-12 | PXD012682 |
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