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MetabolomicsInhibition of anaerobic digestion by various ammonia sources resulted in subtle differences in metabolite dynamics

The impact of ammonia on anaerobic digestion performance and microbial dynamics has been extensively studied, but the concurrent effect of anions brought by ammonium salt should not be neglected. This paper studied this effect using metabolomics and a time-course statistical framework. Metabolomi...

2024-03-01 | MTBLS7859 | MetaboLights
MetabolomicsGenetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway (Part 1)
Not available
ORGANISM(S): Plasmodium falciparum 
ST002106 | MetabolomicsWorkbench
MetabolomicsGenetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway (Part 3)
Not available
ORGANISM(S): Plasmodium falciparum 
ST002108 | MetabolomicsWorkbench
MetabolomicsGenetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway (Part 2)
Not available
ORGANISM(S): Plasmodium falciparum 
ST002107 | MetabolomicsWorkbench
ProteomicsHydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization
The extracellular matrix (ECM) is readily enriched by decellularizing tissues with non-denaturing detergents to solubilize and deplete the vast majority of cellular components. This approach has been used extensively to generate ECM scaffolds for regenerative medicine technologies and in 3D cell cul...
ORGANISM(S): Mus musculus (Mouse) 
2017-10-20 | PXD006428 | Pride
Proteomics Mass spectrometry Lc-srm Matrisome Tissue extraction Collagen Chemical digestion Extracellular matrix 
MetabolomicsA large-scale metabolomics study to harness chemical diversity and explore biochemical mechanisms in ryegrass (UPLC-MS C1 reverse phase POS and GC-MS FAME assays)
Perennial ryegrass (Lolium perenne) is integral to temperate pastoral agriculture, which contributes most of the milk and meat production worldwide. Chemical profiles and diversity of ryegrass offer several opportunities to harness specific traits and elucidate underlying biological mechanism...
2019-03-01 | MTBLS66 | MetaboLights
TranscriptomicsDirect reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails
The direct conversion, or trans-differentiation, of non-cardiac cells into cardiomyocytes by forced expression of transcription factors and microRNAs provide promising ways of cardiac regeneration. However, genetic manipulations are still not desirable in real clinical applications. we report the ge...
ORGANISM(S): Mus musculus 
2015-08-23 | E-GEOD-69924 | biostudies-arrayexpress
GenomicsSingle-CpG resolution mapping of 5-hydroxymethylcytosine by chemical labeling and exonuclease digestion (SCL-exo)
We report the setup of a new method to map 5-hydroxymethylcytosine (5hmC) genome-wide at CpG resolution. The method combines selective chemical labeling by 5hmC b-glucosyltransferase and exonuclease digestion of the DNA molecules bound to streptavidin beads after biotinylation of the 5-glucosylmethy...
ORGANISM(S): Mus musculus 
2016-03-04 | GSE70635 | GEO
ProteomicsChemical acetylation of ligands and two-step digestion protocol for reducing co-digestion in affinity purification-mass spectrometry
We present an effective, fast and user-friendly method to reduce co-digestion of bead-bound ligands, such as antibodies or streptavidin, in affinity purification-mass spectrometry experiments. A short pre-incubation of beads with Sulfo-NHS-Acetate leads to chemical acetylation of lysine residues, ma...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2023-10-23 | PXD043709 | Pride
Chemical acetylation Immunopurification Streptavidin Ligand Affinity purification Sulfo-nhs-acetate Nanobody Gfp 
UnknownImpact of In vitro Gastrointestinal Digestion on the Chemical Composition and Prebiotic Potential of Coffee Silverskin.
Not available
S-EPMC12413342 | biostudies-literature
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