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Since PRSS35 only exhibited tumor suppressive effects in mice, but not in the cultured cells, we speculated that some factors in the microenvironment are affected by PRSS35. To explore this possibility, we performed SILAC proteomic analysis in conjunction with RNA sequencing to identify secreted pro...
ORGANISM(S): Homo sapiens (Human) 
2023-02-15 | PXD033579 | Pride
To identify potential factors related to the development and progression of HCC, we employed label-free proteomic analysis of the HCC secretome and compared the protein profiles of human PLC liver cancer cells with that of human THLE3 hepatocytes secreted in conditioned medium.
ORGANISM(S): Homo sapiens (Human) 
2023-02-15 | PXD033437 | Pride
Using a whole-genome oligonucleotide microarray designed based on known and predicted indica rice genes, we investigated transcriptome profiles in developing leaves and panicles of super hybrid rice LYP9 and its parental cultivar 93-11 and PA64s. We detected 22,266 expressed genes out of 36,926 tota...
ORGANISM(S): Oryza sativa 
Abnormal Notch1 expression has an important role in tumorigenesis. However, upstream control mechanisms for Notch1 are still insufficiently understood. Acute myeloid leukemia (AML) is one of the most common and lethal blood malignancies with limited possibilities for treatment. Thus, new therapeutic...
ORGANISM(S): Homo Sapiens 
2024-10-03 | PXD056593 |
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