Sort   by:  
 Page size 
ProteomicsSILAC proteomic analysis of secreted proteins from PLC cells expressing EV or PRSS35
Since PRSS35 only exhibited tumor suppressive effects in mice, but not in the cultured cells, we speculated that some factors in the microenvironment are affected by PRSS35. To explore this possibility, we performed SILAC proteomic analysis in conjunction with RNA sequencing to identify secreted pro...
ORGANISM(S): Homo sapiens (Human) 
2023-02-15 | PXD033579 | Pride
Ev Prss35 Plc Secreted proteins 
ProteomicsBioID screen for PRSS35 interactors in human primary fibroblasts
We identified the serine protease PRSS35 as a major player in the response to hyperosmotic stress. To gain insight into the mechanisms of action of PRSS35 in human primary fibroblasts, we searched for PRSS35-BirA-HA proximal proteins using BioID interaction screening.
ORGANISM(S): Homo sapiens (Human) 
2023-08-03 | PXD042894 | Pride
Human Q-exactive hf Primary fibroblasts Bioid 
GenomicsSubstrates of PRSS35 in PLC cells
Substrates of PRSS35 in PLC cells
PRJNA830851 | ENA
TranscriptomicsSubstrates of PRSS35 in PLC cells
Since PRSS35 only exhibited tumor suppressive effects in mice, but not in the cultured cells, we speculated that some factors in the microenvironment are affected by PRSS35. To explore this possibility, we performed SILAC proteomic analysis in conjunction with RNA sequencing to identify secreted pro...
ORGANISM(S): Homo sapiens 
2023-02-15 | GSE201311 | GEO
UnknownCorrelation of cumulus gene expression of GJA1, PRSS35, PTX3, and SERPINE2 with oocyte maturation, fertilization, and embryo development.
Not available
S-EPMC4537566 | biostudies-literature
ProteomicsEffects of PRSS35 on the extra cellular matrix
In the project four sets of label-free proteomics studies were performed to characterize the extra cellular matrix (ECM) proteome of differentially treated cells (see below). All cells were treated with sorbitol to induce the expression of PRSS35. Only in set IV PRSS35 is downregulated. For each set...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD040684 | Pride
Human Ecm Lc-msms Skin Fibroblast 
UnknownSerine protease 35 regulates the fibroblast matrisome in response to hyperosmotic stress.
Not available
S-EPMC10468140 | biostudies-literature
UnknownNovel cleft susceptibility genes in chromosome 6q.
Not available
S-EPMC2924960 | biostudies-literature
UnknownIdentification of a novel tumour microenvironment-based prognostic biomarker in skin cutaneous melanoma.
Not available
S-EPMC8642691 | biostudies-literature
TranscriptomicsEffect of prenatal sulforaphane (SUL) on hyperoxia-induced lung injury in Nrf2+/+ and Nrf2-/- neonates
Results: Prenatal SUL altered baseline lung genes involved in organ/cell development and grow (e.g., Ibsp, Ctsk, Igfbp5) and ARE responses (e.g., Aldh3a1, Maff, Mafg) in Nrf2+/+ neonates and in cell morphogenesis and cell death and organismal injury/abnormality inhibition (e.g., Neat1, Nox4, Vegfa, ...
ORGANISM(S): Mus musculus 
2022-01-05 | GSE164699 | GEO
Sort   by:  
 Page size