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We are using the immunoprecipitation coupled with mass spectrometry to identify additional components of the Arabidopsis Hrd1-containing ERAD complex
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-08-15 | PXD013400 | Pride
We reported a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics and phosphoproteomics profiling, of 448 trace-tumor-samples from 190 urothelial bladder neoplasm patients, covering the whole spectrum of disease stages and grades. DNA damage was a...
ORGANISM(S): Homo Sapiens 
We collected 3 replicates of whole stomach organs at 15 time points that covered embryonic days (E12.5, E13.5, E14.5, E15.5, E16.5, E17.5, E18.5), postnatal days (D1, D3, D5), and postnatal weeks (W1, W2, W3, W6, W8). The sampling time window covered from the earliest day that stomach sampling is an...
ORGANISM(S): Mus Musculus 
licorice-yuanhua is one of the incompatible herbal pairs in the "Eighteen incompatible Medicaments" of traditional Chinese Medicine. In this study, Chemical compounds in licorice and yuanhua were used to treat the LS174T cells and iTRAQ labled proteomics study was conducted.
ORGANISM(S): Homo Sapiens 
2020-04-09 | PXD018456 |
The phenotype of β-thalassemia underlies multigene interactions, making clinical stratification complicated. An increasing number of genetic modifiers affecting the disease severity have been identified, but are still unable to meet the demand of precision diagnosis. Here, we systematically conducte...
ORGANISM(S): Homo Sapiens 
2022-03-10 | PXD032179 |
Here, we performed plasma extracellular vesicles (EVs) proteomics on 20 β-thalassemia major (TM) patients, 20 intermedia (TI) patients, and 20 healthy controls to explore the subgroup characteristics and the potential biomarkers. The proteome of paired plasma was analyzed in parallel to compare the ...
ORGANISM(S): Homo Sapiens 
2022-06-15 | PXD034548 |
The human gastric mucosa is the most active and functional layer that carries out food digestion and metabolic processes in physiological conditions and also the main origin of carcinogenesis in gastric cancer. Anatomically, the human stomach is divided into 7 regions with physiological functions, b...
ORGANISM(S): Homo Sapiens 
2018-11-26 | PXD011821 |
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole genome sequencing of tumour and normal DNA from 12 children with ETP ALL and assessed the frequency of somatic alterations in 52 ETP and 42 non-ETP T-ALL samples by...
ORGANISM(S): Homo sapiens 
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