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ProteomicsFrizzled4 proximity interactors
Frizzled4 (FZD4) is a pivotal receptor for Norrin and Wnt7a/b that mediates CNS angiogenesis, blood-brain barrier function and blood-retina barrier function. FZD4 is a target for pharmacological interventions in retinal and neurological disease. In order to understand mechanisms of regulation of Fri...
ORGANISM(S): Homo sapiens (Human) 
2026-05-15 | PXD065058 | Pride
Fzd4 Hela Hek293t Bioid Lc-ms/ms 
MetabolomicsEvaluation of sample preparation methods for NMR-based metabolomics of cow milk
The quality of milk metabolome analyzed by nuclear magnetic resonance (NMR) is greatly influenced by the way samples are prepared. Although this analytical method is increasingly used to study milk metabolites, a thorough examination of available sample preparation protocols for milk has not been re...
2019-06-13 | MTBLS623 | MetaboLights
UnknownSurface hydroxide promotes CO2 electrolysis to ethylene in acidic conditions.
Not available
S-EPMC10130127 | biostudies-literature
UnknownHypertonic Dextrose Stimulates Chondrogenic Cells to Deposit Collagen and Proliferate.
Not available
S-EPMC8804764 | biostudies-literature
UnknownA Frizzled4-LRP5 agonist promotes blood-retina barrier function by inducing a Norrin-like transcriptional response.
Not available
S-EPMC10407957 | biostudies-literature
UnknownTSPAN12 Is a Norrin Co-receptor that Amplifies Frizzled4 Ligand Selectivity and Signaling.
Not available
S-EPMC5533581 | biostudies-literature
UnknownThe MDM2-p53 axis regulates norrin/frizzled4 signaling and blood-CNS barrier function.
Not available
S-EPMC12288884 | biostudies-literature
ProteomicsSupercooled, subzero, high salinity incubations of Cp34H reveal long-term mitigation strategies and detectable (peptide) biomarkers for life on other icy worlds
Colwellia psychrerythraea is a marine psychrophilic bacterium known for its remarkable ability to maintain activity during long-term exposure to extreme subzero temperatures and correspondingly high salinities in sea ice. These microorganisms must have simultaneous adaptations to high salinity and l...
ORGANISM(S): Colwellia psychrerythraea 34H 
2022-02-16 | PXD022428 | Pride
Proteomics Cp34h Culturability Life detection Sea-ice Biomarkers Psychrophile Arctic Subzero 
UnknownThe Calcium Pump ATP2B1/PMCA1 Regulates CNS Vascular Development by Facilitating Norrin- and WNT7A/B-induced Frizzled4 signaling.
Not available
S-EPMC12330718 | biostudies-literature
UnknownC1q limits cystoid edema by maintaining basal beta-catenin-dependent signaling and blood-retina barrier function.
Not available
S-EPMC12330627 | biostudies-literature
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