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MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
ProteomicsStomatin modulates adipogenesis through ERK pathway and regulates fatty acid uptake and lipid droplet growth
Controlling fatty acid uptake, lipid production and storage, and metabolism of lipid droplets (LDs), is closely related to lipid homeostasis, adipocyte hypertrophy and obesity. We report here that stomatin, a major constituent of lipid rafts, participates in adipogenesis and adipocyte maturation by ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-05 | PXD031866 | Pride
Erk pathway Adipogenesis 3t3-l1 adipocyte-like cell 
UnknownTang Wang Ming Mu Granule Attenuates Diabetic Retinopathy in Type 2 Diabetes Rats.
Not available
S-EPMC5742249 | biostudies-literature
UnknownA long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages.
Not available
S-EPMC6191062 | biostudies-literature
UnknownSurface TREM2 on circulating M-MDSCs as a novel prognostic factor for adults with treatment-naive diffuse large B-cell lymphoma.
Not available
S-EPMC10080769 | biostudies-literature
ProteomicsER-associated degradation of Eag1 potassium channels by the RING E3 ubiquitin ligase MKRN1: the presence of a dual ubiquitination system
Mutations in the human gene encoding the neuron-specific Eag1 voltage-gated K+ channel are associated with neurodevelopmental diseases, indicating an important role of Eag1 during brain development. A disease-causing Eag1 mutant channel is linked to defective protein stability that involves enhanced...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023984 | Pride
Ring e3 Mkrn1 
UnknownNetwork Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer's Disease.
Not available
S-EPMC7774966 | biostudies-literature
ProteomicsStreptococcus agalactiae LC-MSMS
The human-derived serotype Ⅴ ST1 GBS strains NNA038 and NNA048 was isolated from a amniotic fluid of full-term pregnant woman who suffered from premature rupture of membrane in China.Serotype Ia ST7 GBS strain YM001 is an attenuated strain ,its parent strain HN016 was isolated from an outbreak epide...
ORGANISM(S): Streptococcus agalactiae 
2019-11-12 | PXD011206 | Pride
Human Tilapia Streptococcus agalactiae Lc-msms 
UnknownOncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings.
Not available
S-EPMC5312391 | biostudies-literature
UnknownMitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors.
Not available
S-EPMC5732754 | biostudies-literature
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