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MetabolomicsTidal filtering drives microbiome assembly and metabolic coupling in desiccation-tolerant red algae


This study investigates how the intertidal red alga Pyropia haitanensis (Bangiophyceae) achieves rapid desiccation-rehydration tolerance through coordinated interactions between the host, its associated microbiome, and key metabolites. By integrating 16S rRNA amplicon sequencing, metag...

2026-05-07 | MTBLS13613 | MetaboLights
MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
ProteomicsProteomics reveals the function reverse of MPSSS treated prostate cancer-associated fibroblasts to suppress PC-3 cell viability via the FoxO pathway
Prostate cancer (PCa) remains the malignancy with the highest morbidity in men (1). Although early-stage PCa usually causes no symptoms, cancer cells in prostate glands readily metastasize to bones, lymph nodes, lungs, and liver during PCa progression (2). Common strategies, including surgery, radia...
ORGANISM(S): Homo sapiens (Human) 
2021-03-22 | PXD023689 | Pride
Human Proteomics Prostate cafs Secretomics Prostate cancer cells Lc-ms/ms 
ProteomicsProteomic analysis of mouse samples including the bEnd.3 cells conditioned mediums and treated primary astrocytes.
10 samples which include the bEnd.3 cells conditioned medium and treated primary astrocytes were analyzed with LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2026-03-26 | PXD036816 | Pride
TranscriptomicsFetal lung development
Fetal lung development is a complex biological process, which involves temporal and spatial regulations of many genes. To understand molecular mechanisms of this process, we investigated gene expression profiling of lungs at gestational day 18, 19, 20, 21, new born, and adult rats using in-house rat...
ORGANISM(S): Rattus norvegicus 
2010-07-01 | E-GEOD-3302 | biostudies-arrayexpress
TranscriptomicsMicroRNA signatures in human cervical cancer
Our study investigates miRNAs might play a role in the pathogenesis of cervical cancer and identify altered miRNA gene methylation as a possible epigenetic mechanism involved in their aberrant expression. Cervical cancer cells were seeded at low density and cultured for 48 h. Experimental groups wer...
ORGANISM(S): Homo sapiens 
2011-10-10 | E-GEOD-32724 | biostudies-arrayexpress
ProteomicsiTRAQ-based analysis of muscle mitochondria isolated from LONP1-mKO mice
This experiment was conducted to identify the mitochondrial protein changes in the presence and absence of LONP1 in skeletal muscle. The following abstract from the submitted manuscript describes the major findings of this work.Disuse-associated loss of muscle LONP1 impairs mitochondrial quality and...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-05 | PXD029722 | Pride
Mouse Skeletal muscle 
ProteomicsK562 cell lime LC-MSMS,Quantitative measurement of hydrophobicity dependent LLPS property of chromatin condensate
K562 cell line treated with 1,6-HD and proteins were captured via cross-linking. We quantified chromatin structure changes and chromatin binding proteins in K562 cell before and after 1,6-hexanediol treatment by Hi-C and Hi-MS, respectively.
ORGANISM(S): Homo sapiens (Human) 
2021-07-26 | PXD021434 | Pride
K562 Lc-msms 
ProteomicsK562 cell line LC-MSMS,Quantitative measurement of hydrophobicity dependent LLPS property of chromatin condensate
K562 cell line treated with 2,5-HD and proteins were captured via cross-linking. We quantified chromatin structure changes and chromatin binding proteins in K562 cell before and after 2,5-hexanediol treatment by Hi-C and Hi-MS, respectively.
ORGANISM(S): Homo sapiens (Human) 
2021-07-26 | PXD027565 | Pride
Human K562. llps 
TranscriptomicsArsenic-induced Changes in L2 Cells
Arsenic is a carcinogen that is known to induce cell transformation and tumor formation. Although studies have been performed to examine the modulation of signaling molecules caused by arsenic exposure, the molecular mechanisms by which arsenic causes cancer are still unclear. We hypothesized that ...
ORGANISM(S): Rattus norvegicus 
2011-12-23 | E-GEOD-9790 | biostudies-arrayexpress
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