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MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
ProteomicsProteomics of adult and metacercariae of Metorchis orientalis
We used proteomics to compare the differential protein expression between adult and metacercariae stage of Metorchis orientalis. Three biological replicates were set up at each stage for protein analysis using Nano HPLC.
ORGANISM(S): Metorchis Orientalis 
PXD029022 |
ProteomicsProteogenomic characterization analysis of human large cell lung cancer
Current clinical therapy of non-small cell lung cancer depends on histo-pathological classification. This approach poorly predicts clinical outcome for individual patients. Proteogenomic characterization analysis holds promise to improve clinical stratification, thus paving the way for individualize...
ORGANISM(S): Homo Sapiens 
2019-01-16 | PXD012393 |
ProteomicsProteomic analysis of Emx1-G6PD CKO mouse cortex
To identify differentially expressed proteins in the cerebral cortex between control and Emx1-G6PD CKO mice
ORGANISM(S): Mus Musculus 
PXD066386 |
UnknownCharacterization of the extrinsic and intrinsic signatures and therapeutic vulnerability of small cell lung cancers.
Not available
S-EPMC12420805 | biostudies-literature
ProteomicsProteins that bind to IGFBP7 in cadmium-induced hepatorenal fibrosis
Through liquid chromatography-mass spectrometry (LC-MS/MS) analysis, we analyzed the differential proteins in cadmium-induced mouse kidney and liver tissues, and looked for the potential targets of IGFBP7
ORGANISM(S): Mus Musculus 
PXD057126 |
ProteomicsHK1 from HSC-derived extracellular vesicles promotes HCC progression
Extracellular vesicles play crucial roles in intercellular communication in tumor microenvironment. Here, we demonstrate that in hepatic fibrosis, TGF-β stimulates the palmitoylation of hexokinase 1 (HK1) in hepatic stellate cells (HSCs), which facilitates the secretion of HK1 via large extracellula...
ORGANISM(S): Homo Sapiens 
PXD035911 |
UnknownMetabolic dysfunction-associated steatotic liver disease accelerates pancreatic cancer progression and metastasis via the macrophage migration inhibitory factor-CD44 axis.
Not available
S-EPMC12811260 | biostudies-literature
ProteomicsThe pan-cancer lncRNA PLANE regulates an alternative splicing program and promotes cancer pathogenesis
Proteome analysis of Biotin- PLANE pull-down assays
ORGANISM(S): Homo Sapiens 
2020-11-26 | PXD022747 |
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
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