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A comparison of gene expression in the mammary gland of lactating mice at day 9 after parturition between Akt -/- and wildtype individuals.
ORGANISM(S): Mus musculus 

INTRODUCTION: Bariatric surgery is known to be the most effective treatment for weight loss in obese patients and for the rapid remission of obesity-related comorbidities. These short-term improvements result from not only limited digestion or absorption but also dynamic changes ...

2022-03-17 | MTBLS2472 | MetaboLights
The direct inflammatory action of proprotein convertase subtilisin/kexin type 9 (PCSK9) is examined in vitro in monocytes and endothelial cells, as well as via an in vivo atherosclerosis animal model. PCSK9 exacerbates atherosclerosis in low-density lipoprotein receptor (LDLR)-/- mice, indicating an...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD047058 | Pride
Overwhelming and persistent inflammation of retinal pigment epithelium (RPE) induces destructive changes in retinal environment by invoking immune activation. In this study, we aimed to investigate RPE-specific biological and metabolic response against intense inflammation, and identify molecular ch...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018260 | Pride
Overwhelming and persistent inflammation of retinal pigment epithelium (RPE) induces destructive changes in retinal environment by invoking immune activation. In this study, we aimed to investigate RPE-specific biological and metabolic response against intense inflammation, and identify molecular ch...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018257 | Pride
UBR4 was identified as a potential oncogene in lung adenocarcinoma (LUAD). In this study, we performed a quantitative proteomics analysis using tandem mass tag (TMT) 6-plex technology in UBR4 knockout A549 cell lines to discover an essential role of UBR4 in tumor growth and metastasis.
ORGANISM(S): Homo sapiens (Human) 
2025-06-03 | PXD051417 | Pride
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