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ProteomicsProteomic dynamic changes in HDL subfractions from mouse plasma
HDL proteome dynamics may determine HDL cardioprotective functions. We aimed to characterize proteome and lipid profiles in small, medium and large (S/M/L) HDL fractions and analyze their functions. We characterized mouse HDL fractions by their high phospholipid (PL) content and collected S/M/L-HDL...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD011185 | Pride
Plasam Mouse Esi-ms/ms Hdl subfractions Hdl 
UnknownHDL subclass proteomic analysis and functional implication of protein dynamic change during HDL maturation.
Not available
S-EPMC6541906 | biostudies-literature
TranscriptomicsThe genomic responses of mouse liver to diclofenac treatment reveals an immune mediated mechanism of liver injury
Diclofenac (DCL) is a non-steroidal anti-inflammatory drug. Its use can be associated with serious adverse drug reactions most notable myocardial infarction and drug-induced liver injury (DILI). The molecular causes leading to DILI remains unclear and it seems to be multifactorial. The aims of this ...
ORGANISM(S): Mus musculus 
2016-08-09 | E-GEOD-75277 | biostudies-arrayexpress
Genomicsena-DATASET-asan-ccgd-27-09-2019-00:22:21:191-59 - samples
231 HCC exome sequencing with Sureselect 50Mb
EGAD00001005361 | EGA
GenomicsThese are from Korean HCC samples with exome sequencing
Hepatic resection is the most curative treatment option for early-stage hepatocellular carcinoma, but is associated with a high recurrence rate, which exceeds 50% at 5 years after surgery. Understanding the genetic basis of hepatocellular carcinoma at surgically curable stages may enable the identif...
EGAS00001000604 | EGA
Genomicswhole exome sequencing of Korean hepatocellular carcinomas
Data Access Committee EGAC00001000329
EGAC00001000329 | EGA
TranscriptomicsmiR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4
we identified novel age-related microRNAs through comparative analysis of miRNA expression profiles in young and old myoblasts using next generation sequencing (NGS) small RNA profiles of young mouse and old mouse were generated by deep sequencing, in each four samples, using Illumina GAIIx
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-66267 | biostudies-arrayexpress
ProteomicsBioID-MS of TBX3-proximal proteins in HEK293T cells
Wnt signaling orchestrates gene expression in a plethora of processes during development and adult cell homeostasis via the action of nuclear b-catenin. Yet, little is known about how b-catenin generates context-specific transcriptional outcomes. Addressing this knowledge gap is pivotal since neopla...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD047899 | Pride
Tbx3 Hek293t Wnt Bioid 
UnknownNon-invasive skin sampling detects systemically administered drugs in humans.
Not available
S-EPMC9321436 | biostudies-literature
ProteomicsHistone serotonylation regulates ependymoma tumorigenesis through neurodevelopmental pathways
Bidirectional communication between tumors and neurons has emerged as a key facet of the tumor microenvironment that drives malignancy. Another hallmark feature of cancer is epigenomic dysregulation, where alterations in gene expression influences cell states and interactions with the tumor microenv...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-09 | PXD048170 | Pride
Epigenetic regulation Zfta-rela ependymoma Cancer neuroscience Developmental transcription factor 
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