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This study aimed to characterize proteins bound to the extracorporeal membrane oxygenation (ECMO) circuit primed with albumin and crystalloid solution, as per standard clinical protocol.
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD050399 | Pride
Replication protein A (RPA) is a heterotrimeric single-strand DNA binding protein that is integral to DNA metabolism. Segregation of RPA functions in response to DNA damage is fine-tuned by hyperphosphorylation of the RPA32 subunit that is dependent on Cyclin-dependent kinase (Cdk)-mediated priming ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD068080 | Pride
Differential responses to stimuli can affect how cells succumb to disease. In yeast, DNA damage can create heterogeneous responses. To delineate how a response contributes to a cell's future behavior, we constructed a transcription-based memory circuit that detects DNA repair to isolate subpopulatio...
ORGANISM(S): Saccharomyces cerevisiae 
A circuit of mechanically regulated transcription factors balances regenerative and fibrotic memory of mesenchymal stromal cells [RNA-seq]
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