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ProteomicsFunction of clpF in the clp protease complex
The plant plastid Clp machinery comprises a hetero-oligomeric ClpPRT proteolytic core, ATP-dependent ClpC,D chaperones and an adaptor protein, ClpS1. ClpS1 directs a subset of substrates to the Clp protease-chaperone complex for degradation, but substrate recognition and delivery mechanisms are unkn...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-09 | PXD002186 | Pride
Lc-msms Plant cell Arabidopsis thaliana Coip Clp complex Chloroplast Stroma 
TranscriptomicsTranscription profiling of four mouse bone marrow hematopoietic stem cells (HSC) early B lineage stages(MLP, CLP, Fr.A, Fr.B) to identify coordinately regulated gene as cells progress down the B cell development pathway
Differentiation from hematopoietic stem cells (HSC) to early B-lineage cells proceeds through a series of intermediate stages, during which cells are thought to become progressively more restricted in their developmental potential. RNAs were prepared from four early B lineage stages(MLP, CLP, Fr.A, ...
ORGANISM(S): Mus musculus 
2006-12-16 | E-MEXP-559 | biostudies-arrayexpress
ProteomicsTime-resolved inducible knock-down of Clp protease subunits in tobacco identifies putative protease substrates
The Clp protease complex in plants is the one with the highest complexity through all life kingdoms. It is composed of 14 nuclear- and plastid-encoded subunits which are allocated in different rings across the complex. The proteolytic ring (P-ring; ClpP3-ClpP6) and non-proteolytic ring (R-ring; ClpR...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-22 | PXD008305 | Pride
Clp protease  chloroplast  protein degradation  protease substrate  nicotiana tabacum  inducible rnai  lc-msms  shotgun proteomics 
TranscriptomicsExpression data from WT, HEB-KO and E2A-KO LY6D- CLP cells
The E-protein transcription factors E2A and HEB play important roles at several stages of hematopoiesis. However, the exact mechanism for theire action and the main targets in the LY6D negative common lymphoid progentior (CLP) compartment remains unknown. By adressing this question, we will gain imp...
ORGANISM(S): Mus musculus 
2011-11-22 | E-GEOD-27402 | biostudies-arrayexpress
UnknownAntibiotic Acyldepsipeptides Stimulate the Streptomyces Clp-ATPase/ClpP Complex for Accelerated Proteolysis.
Not available
S-EPMC9765437 | biostudies-literature
TranscriptomicsThe Mycobacterium tuberculosis Clp Gene Regulator is Required for in vitro Reactivation from Hypoxia-induced Dormancy
The isogenic Mtb:ΔRv2745c mutant is significantly more sensitive normoxia conditions after a period of hypoxia, relative to wild-type Mtb, implicating a role for ClgR in response to reactivation, in vivo. Both hypoxia and reaeration treatment led to dysregulation of the σH regulon in the isogenic mu...
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2014-12-12 | E-GEOD-64065 | biostudies-arrayexpress
UnknownPfClpC Is an Essential Clp Chaperone Required for Plastid Integrity and Clp Protease Stability in Plasmodium falciparum.
Not available
S-EPMC5726808 | biostudies-literature
TranscriptomicsGenes affected by Satb1 deficiency in HSC, LMPP and CLP
To understand gene expression signatures between wild-type and Satb1-deficient cells To examine genes regulated by Satb1 expression, sets of microarrays were conducted with Lin- c-kitHi Sca-1+ Flt3- HSC-enriched cells, Lin- c-kitHi Sca-1+ Flt3+LMPP-enriched cells, and Lin- c-kitLo Sca-1Lo IL7Rα+ C...
ORGANISM(S): Mus musculus 
2013-03-20 | E-GEOD-45299 | biostudies-arrayexpress
UnknownGeneration and characterization of a collection of knock-down lines for the chloroplast Clp protease complex in tobacco.
Not available
S-EPMC5447895 | biostudies-literature
UnknownStructural insights into the Clp protein degradation machinery.
Not available
S-EPMC11005422 | biostudies-literature
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