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TranscriptomicsmRNA Expression Changes with Cofilin-2 Deficiency
mRNA Expression in Quadriceps Muscle from Cofilin-2 Null Mice Compared to WT Littermates on Day 7 Quadriceps muscle resected on day 7 from cofilin-2 deficient mice and wildtype littermates were collected and mRNA was isolated. Expression changes were analyzed by microarray.
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-61404 | biostudies-arrayexpress
TranscriptomicsmiRNA Expession Changes with Cofilin-2 Deficiency
miRNA Expression in Quadriceps Muscle from Cofilin-2 Null Mice Compared to WT Littermates on Day 7 Quadriceps muscle resected on day 7 from cofilin-2 deficient mice and wildtype littermates were collected and mIRNA was isolated. Expression changes were analyzed by microarray.
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-61449 | biostudies-arrayexpress
ProteomicsIdentification of MELK-mediated Cofilin-1 T70 phosphorylation by IP-LC-MS/MS analysis
To investigate whether MELK phosphorylates Cofilin-1 at residue Threonine 70 (T70), we performed a phosphoproteomic validation using immunoprecipitation coupled with mass spectrometry (IP-LC-MS/MS). HEK293T cells were divided into three experimental groups: (1) MOCK control (Empty Vector), (2) MELK ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-01 | PXD074164 | Pride
Cofilin-1 Melk Immunoprecipitation Affinity purification-ms Otssp167 Hek293t T70 phosphorylation Lc-ms/ms 
ProteomicsC9ORF72 interaction with cofilin modulates actin dynamics in motoneurons
Intronic hexanucleotide expansions in C9ORF72 are common in ALS and FTLD, but it is unknown whether loss of function, toxicity by the expanded RNA or dipeptides from non ATG-initiated translation are responsible for the pathophysiology. We determined the interactome of C9ORF72 in motoneurons and fou...
ORGANISM(S): Mus musculus (Mouse) 
2016-09-30 | PXD004913 | Pride
Ftld Cofilin Als C9orf72 
GenomicsExpression data from heart expressing cofilin-1(Th25) variants
Expression data from heart expressing cofilin-1(Th25) variants
PRJNA906086 | ENA
ProteomicsA quantitative proteomic view of cofilin phosphorylation and its modulation using the LIM kinase inhibitor Pyr1
LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules and the actin cytoskeleton.. Cofilin is the only LIM kinases substrate that is well described to date, and its phosphorylation on serine 3 by LIM Kinases control...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-12-19 | PXD010167 | Pride
Human Cofilin 2d gel Mouse Phosphorylation Lc-ms/ms 
ProteomicsIdentification of N-terminal SUMOylation of mouse cofilin-1 by IP-MS
Small ubiquitin-like modifier (SUMO) typically conjugates to target proteins through isopeptide linkage to the ε-amino group of lysine residues. This posttranslational modification (PTM) plays pivotal roles in modulating protein function. As a key regulator of actin cytoskeleton dynamics, cofilins (...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD038392 | Pride
Mouse Cofilin-1 Ip-ms N-terminal sumoylation 
GenomicsmiRNA Expession Changes with Cofilin-2 Deficiency
miRNA Expression in Quadriceps Muscle from Cofilin-2 Null Mice Compared to WT Littermates on Day 7
ORGANISM(S): Mus musculus 
2015-09-01 | GSE61449 | GEO
TranscriptomicsmRNA Expression Changes with Cofilin-2 Deficiency
mRNA Expression in Quadriceps Muscle from Cofilin-2 Null Mice Compared to WT Littermates on Day 7
ORGANISM(S): Mus musculus 
2015-09-01 | GSE61404 | GEO
GenomicsDistinct functional constraints driving conservation of the cofilin N-terminal regulatory tail
Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail
PRJNA1013251 | ENA
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