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TranscriptomicsToxicogenomic analysis of ionic silver and silver nanoparticles on the fathead minnow and implications to human health
Nanoparticles are compounds of emerging concern with largely unknown risks for human and ecological health. It is crucial to evaluate their potential biological impact to prevent unintended adverse effects on human health and the environment. We analyzed the transcriptional effects of polyvinylpyrro...
ORGANISM(S): Pimephales promelas 
2013-11-01 | E-GEOD-46520 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of dominant follicle development in the equine ovary
The Objective of this study was to establish global gene expression profiles associated with different stages of dominant follicle development in the horse. This was done by collecting ovaries at different stages of an ovulatory follicular wave, when the dominant follicle reached 22 mm (early domi...
ORGANISM(S): Equus caballus 
2014-03-15 | E-GEOD-52109 | biostudies-arrayexpress
TranscriptomicsA genome-wide transcriptome analysis reveals diverse roles of two-component system DraR-K in physiological and morphological differentiation of Streptomyces coelicolor
A novel two-component system (TCS) DraR-K was identified previously to play a differential role in antibiotic biosynthesis (ACT, RED and yCPK) of Streptomyces coelicolor M145 on defined minimal medium (MM) conditions. In order to assess whether DraR-K has more global roles, a genome-wide transcripto...
ORGANISM(S): Streptomyces coelicolor 
2014-03-10 | E-GEOD-55714 | biostudies-arrayexpress
TranscriptomicsBMP-7 microarray in human articular cartilage
Responses of human adult articular chondrocytes under conditions of lack or excess of bone morphogenetic protein-7 also called osteogenic protein 1. Original processed data file is in E-MTAB-571.additional.zip archive.
ORGANISM(S): Homo sapiens 
2011-03-09 | E-MTAB-571 | biostudies-arrayexpress
TranscriptomicsUsing RNA-Seq for gene identification, polymorphism detection and transcript profiling in two alfalfa genotypes with divergent cell wall composition in stems
Alfalfa, [Medicago sativa (L.) sativa], a widely-grown perennial forage has potential for development as a cellulosic ethanol feedstock. The application of genomic approaches would advance development of alfalfa as a cellulosic feedstock. However, the genomics of alfalfa, a non-model species, is sti...
ORGANISM(S): Medicago sativa 
2011-04-21 | E-GEOD-26757 | biostudies-arrayexpress
UnknownCold-activated brown adipose tissue is an independent predictor of higher bone mineral density in women.
Not available
S-EPMC5572572 | biostudies-literature
no omics definedTranscription profiling of human U-2 osteosarcoma cell lines expressing different glucocorticoid receptor isoforms - time series
Glucocorticoids regulate diverse physiologic processes and synthetic derivatives of these natural hormones are widely used in the treatment of inflammatory diseases. However, chronic administration often triggers insensitivity and serious side effects including osteoporosis. The underlying mechanis...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6711 | biostudies-arrayexpress
GenomicsIndividual-specific and allele-specific chromatin signatures in diverse human populations
This dataset contains DNase-seq data and CTCF ChIP-seq data for 6 lymphoblastoid cell lines. There are 3 cell lines from a YRI trio and 3 lines from a CEU trio (HapMap GM19238, GM19239, GM 19240, GM12891, GM12892, GM12878). For data usage terms and conditions, please refer to http://www.genome.gov/...
ORGANISM(S): Homo sapiens 
2010-03-15 | E-GEOD-19622 | biostudies-arrayexpress
TranscriptomicsMammalian PERIOD complex regulates repair of DSB in active chromatin through anchoring to the nuclear envelope
Repair of DNA Double Strand Breaks produced in transcriptionally active chromatin occurs through a mechanism, Transcription-Coupled DSB repair (TC-DSBR), that is yet poorly characterized. Here, using a screening approach scoring multiple outputs in human cells, we identified the PER complex, a key m...
ORGANISM(S): Homo sapiens 
2025-11-12 | E-MTAB-12712 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver from wild type (WT), RORalphasg/sg, RORgamma-/-, and double knockout animals reveals a regulatory role for RORalpha and RORgamma in Phase I and Phase II Metabolism
Retinoid-related orphan receptors RORalpha and RORgamma are both expressed in liver; however, their physiological functions have not yet been clearly defined. RORalpha1 and RORgamma1, but not RORalpha4, show an oscillatory pattern of expression during circadian rhythm. To obtain insight into the phy...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7564 | biostudies-arrayexpress
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