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UnknownComplexome Profiling: Assembly and Remodeling of Protein Complexes.
Not available
S-EPMC8346016 | biostudies-literature
UnknownAblation of mitochondrial DNA results in widespread remodeling of the mitochondrial complexome.
Not available
S-EPMC8561636 | biostudies-literature
UnknownCOmplexome Profiling ALignment (COPAL) reveals remodeling of mitochondrial protein complexes in Barth syndrome.
Not available
S-EPMC6735710 | biostudies-literature
ProteomicsComplexome profiling of human induced pluripotent stem cells cultured during normoxic versus hypoxic conditions
Human induced pluripotent stem cells (hiPSCs) have become an invaluable tool for studying molecular disease mechanisms on a human genetic background. They can be differentiated into different cell types, including cardiac myocytes. Here, we studied the remodeling of mitochondrial protein complexes o...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD048535 | Pride
Normoxia Complexome remodeling Hypoxia Stem cells 
ProteomicsComplexome profiling of mitochondria to study NDUFAF1 mediated complex I assembly in Yarrowia lipolytica
The aerobic yeast Yarrowia lipolytica is an established model organism to study mitochondrial protein complexes. Here we performed a complexome analysis of intact mitochondria to study the function of NDUFAF1 in the assembly of respiratory complex I. In the ndufaf1 deletion strain the PD module of t...
ORGANISM(S): Yarrowia lipolytica (Candida lipolytica) 
2022-12-21 | PXD033522 | Pride
Protein complexes Assembly 
UnknownHyperbaric oxygen treatment reveals spatiotemporal OXPHOS plasticity in the porcine heart.
Not available
S-EPMC11179111 | biostudies-literature
UnknownComparative analysis of dynamic transcriptomes reveals specific COVID-19 features and pathogenesis of immunocompromised populations.
Not available
S-EPMC11237560 | biostudies-literature
ProteomicsDysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction - spatial tissue proteomics
BACKGROUND: Despite significant advances in acute care medicine, myocardial infarction (MI) remains a predominant cause of premature death and heart failure. In the infarct border zone, cardiomyocytes are exposed to high biomechanical stress that impairs the integrity of the sarcolemmal membrane. He...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-06 | PXD060267 | Pride
Myocardial ischemia Proteomics Cardiomyocytes Connexin-43 Dysferlin Intracellular membranes Myocardial infarction 
ProteomicsDysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction
BACKGROUND: Despite significant advances in acute care medicine, myocardial infarction (MI) remains a predominant cause of premature death and heart failure. In the infarct border zone, cardiomyocytes are exposed to high biomechanical stress that impairs the integrity of the sarcolemmal membrane. He...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-06 | PXD060259 | Pride
Myocardial ischemia Proteomics Cardiomyocytes Connexin-43 Dysferlin Intracellular membranes Myocardial infarction 
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